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Arhgap25
Gene Detail
Symbol

Name
ID
Arhgap25
Rho GTPase activating protein 25
MGI:2443687
Synonyms
A130039I20Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 6
38.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:87458545-87533259 bp, - strand
From VEGA annotation of GRCm38

  74715 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45507  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ARHGAP25
Gene Tree: Arhgap25

Human
homologs
ARHGAP25, Rho GTPase activating protein 25
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 9938
neXtProt AC: NX_P42331

Human Synonyms: HEL-S-308, KAIA0053

Human Chr (Location): 2p13.3; chr2:68710505-68826833 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Spontaneous(1) Targeted(3)
Genomic Mutations involving Arhgap25 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Arhgap25 interacts with 70 markers (Mir10a, Mir10b, Mir30a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Process signal transduction
Function GTPase activator activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (14)    Tissues (2)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 14
cDNA source data(20)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA ARHGAP25 ; Xenbase arhgap25    NEW 
Molecular
reagents
All nucleic(20) cDNA(20)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000023045 (Evidence)
Ensembl Gene Model ENSMUSG00000030047 (Evidence)
Entrez Gene 232201 (Evidence)
UniGene 119564
DFCI TC1581266, TC1717138
DoTS DT.101372008, DT.40178640, DT.481678, DT.91438640
NIA Mouse Gene Index U027579
Consensus CDS Project CCDS20321.1, CCDS20322.1, CCDS71790.1
International Mouse Phenotyping Consortium Status Arhgap25
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023045 VEGA Gene Model | MGI Sequence Detail 74715 C57BL/6J ±  kb
transcript OTTMUST00000055535 VEGA | MGI Sequence Detail 2831 Not Applicable 
polypeptide OTTMUSP00000026601 VEGA | MGI Sequence Detail 648 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(9) UniProt(2)
Polymorphisms
SNPs within 2kb(573 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001849 Pleckstrin homology domain
InterPro IPR011993 Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
InterPro IPR000198 Rho GTPase-activating protein domain
InterPro IPR008936 Rho GTPase activation protein
Protein Ontology PR:000004231 rho GTPase-activating protein 25
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory