Scart2 MGI Mouse Gene Detail - MGI:2443685 - scavenger receptor family member expressed on T cells 2

Symbol

Scart2
Name

scavenger receptor family member expressed on T cells 2
Synonyms

5830411N06Rik

Feature Type

protein coding gene
IDs

MGI:2443685
NCBI Gene: 244234
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr7:139827197-139880649 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 85.29 cM
Mapping Data

1 experiment

SNPs within 2kb

1713 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2443685	protein coding gene	Chr7:139827192-139880649 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0033172	protein coding gene	Chr7:145342522-145395643 (+)
A/J	MGP_AJ_G0033154	protein coding gene	Chr7:141191425-141244670 (+)
AKR/J	MGP_AKRJ_G0033086	protein coding gene	Chr7:145045068-145110802 (+)
BALB/cJ	MGP_BALBcJ_G0033155	protein coding gene	Chr7:140932535-140990093 (+)
C3H/HeJ	MGP_C3HHeJ_G0032869	protein coding gene	Chr7:144842448-144900221 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0033666	protein coding gene	Chr7:150674651-150740641 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0030639	protein coding gene	Chr7:142320767-142379876 (+)
CAST/EiJ	MGP_CASTEiJ_G0032199	protein coding gene	Chr7:137161263-137210067 (+)
CBA/J	MGP_CBAJ_G0032842	protein coding gene	Chr7:155758600-155823717 (+)
DBA/2J	MGP_DBA2J_G0032994	protein coding gene	Chr7:139159080-139212896 (+)
FVB/NJ	MGP_FVBNJ_G0032947	protein coding gene	Chr7:139056790-139110260 (+)
LP/J	MGP_LPJ_G0033088	protein coding gene	Chr7:146875393-146934218 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0032979	protein coding gene	Chr7:156416362-156474912 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0033686	protein coding gene	Chr7:144055672-144117728 (+)
PWK/PhJ	MGP_PWKPhJ_G0031905	protein coding gene	Chr7:132344543-132403484 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0031750	protein coding gene	Chr7:130880268-130935978 (+)
WSB/EiJ	MGP_WSBEiJ_G0032310	protein coding gene	Chr7:144947470-145000160 (+)

Human Ortholog

SCART1, scavenger receptor family member expressed on T cells 1

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SCART1, scavenger receptor family member expressed on T cells 1
Links

HGNC:32411

NCBI Gene ID: 619207

UniProt: Q4G0T1
Chr Location

10q26.3; chr10:133453928-133523558 (+) GRCh38

MGI Vertebrate Homology

Scart2 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: SCART1
Gene Tree

Scart2

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
11 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

5
Endonuclease-mediated

1
Radiation induced

1
Targeted

3
Genomic Mutations

1 involving Scart2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

45 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

10
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

713
Tissues

6
cDNA Data

4
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

GEO

Expression Atlas

less

All Sequences

48
RefSeq

11
UniProt

3
CCDS

CCDS21970.1, CCDS52433.1, CCDS52434.1

Ensembl

ENSMUSG00000054672 (Evidence)
NCBI Gene

244234

			Length	Strain/Species	Flank
genomic	ENSMUSG00000054672	Ensembl Gene Model \| MGI Sequence Detail	53453	C57BL/6J	± kb
transcript	ENSMUST00000164583	Ensembl \| MGI Sequence Detail	3342	Not Applicable
polypeptide	ENSMUSP00000131905	Ensembl \| MGI Sequence Detail	1112	Not Applicable

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UniProt

3 Sequences
InterPro Domains

IPR001190 SRCR domain

IPR036772 SRCR-like domain superfamily

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All nucleic 4

cDNA 4

Microarray probesets 1

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MGI:6455773

Summaries

All 29

Developmental Gene Expression 1

Gene Ontology 6

Phenotypes 11
Earliest

J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Scart2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr69810	Chr7:139827063-139827088 (+)	-121 bp
Tssr69811	Chr7:139827180-139827227 (+)	7 bp
Tssr69812	Chr7:139827229-139827232 (+)	34 bp
Tssr69813	Chr7:139841393-139841410 (+)	14,205 bp
Tssr69814	Chr7:139852408-139852422 (+)	25,218 bp
Tssr69815	Chr7:139867877-139867891 (+)	40,687 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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