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Sipa1l1 Gene Detail
Summary
  • Symbol
    Sipa1l1
  • Name
    signal-induced proliferation-associated 1 like 1
  • Synonyms
    4931426N11Rik, mKIAA0440, Spar
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443679
    NCBI Gene: 217692
  • Gene Overview
    MyGene.info: SIPA1L1
Location & Maps
more
  • Sequence Map
    Chr12:82170016-82451782 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      281767 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 38.14 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SIPA1L1, signal induced proliferation associated 1 like 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SIPA1L1, signal induced proliferation associated 1 like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    E6TP1
  • Links
    NCBI Gene ID: 26037
    neXtProt AC: NX_O43166

  • Chr Location
    14q24.2; chr14:71321396-71741229 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    71
  • Chemically induced (other)
    1
  • Gene trapped
    68
  • Targeted
    2
  • Genomic Mutations
    1 involving Sipa1l1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042700 Ensembl Gene Model | MGI Sequence Detail 281767 C57BL/6J ±  kb
transcript ENSMUST00000053969 Ensembl | MGI Sequence Detail 7488 Not Applicable  
polypeptide ENSMUSP00000061014 Ensembl | MGI Sequence Detail 1782 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1788 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000014881 signal-induced proliferation-associated 1-like protein 1
  • InterPro Domains
    IPR001478 PDZ domain
    IPR000331 Rap GTPase activating protein domain
    IPR030770 Signal-induced proliferation-associated 1-like protein 1
    IPR021818 Signal-induced proliferation-associated 1-like protein, C-terminal
Molecular
Reagents
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  • All nucleic 123
    cDNA 123

    Microarray probesets 8
Other
Accession IDs
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MGI:2145019
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:202746 Mihalas AB, et al., Opposing action of nuclear factor kappaB and Polo-like kinases determines a homeostatic end point for excitatory synaptic adaptation. J Neurosci. 2013 Oct 16;33(42):16490-501

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory