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Ccdc66
Gene Detail
 Symbol
Name
ID
Ccdc66
coiled-coil domain containing 66
MGI:2443639
Synonyms E230015L20Rik
Feature Type protein coding gene
Genetic Map
Chromosome 14
16.51 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:27482412-27508460 bp, - strand
From Ensembl annotation of GRCm38

  26049 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:35309  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ccdc66

Human
homologs
Human Homolog CCDC66, coiled-coil domain containing 66
NCBI Gene ID 285331
neXtProt AC  NX_A2RUB6
Human Chr (Location)  3p14.3; chr3:56557156-56621836 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display slowly progressing photoreceptor degeneration.
 
Human Diseases Modeled Using Mouse Ccdc66 (1)    Alleles Annotated to Human Diseases(1)   
Interactions
Ccdc66 interacts with 70 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process post-embryonic retina morphogenesis in camera-type eye, retinal rod cell development
Component cellular_component
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (71)    Tissues (37)    Images (18)
Theiler Stages: 23, 26, 28
Assay TypeResults
RNA in situ 71
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000046753 (Evidence)
Entrez Gene320234 (Evidence)
DFCITC1581129, TC1585329, TC1596483
DoTSDT.101226199, DT.94129024, DT.94226106, DT.97393935, DT.99838851
NIA Mouse Gene IndexU035342
Consensus CDS ProjectCCDS36843.1
International Mouse Knockout Project StatusCcdc66
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046753 Ensembl Gene Model | MGI Sequence Detail 26049 C57BL/6J ±  kb
transcript ENSMUST00000050480 Ensembl | MGI Sequence Detail 2940 Not Applicable 
polypeptide ENSMUSP00000052546 Ensembl | MGI Sequence Detail 935 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(12) UniProt(1)
Polymorphisms SNPs within 2kb(85 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000029334 coiled-coil domain-containing protein 66
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:174954 Gerding WM, et al., Ccdc66 null mutation causes retinal degeneration and dysfunction. Hum Mol Genet. 2011 Sep 15;20(18):3620-31
All references(28)
Disease annotation references (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory