Ccdc66
Gene Detail

Symbol Name ID

Ccdc66 coiled-coil domain containing 66 MGI:2443639

Synonyms

E230015L20Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 14

16.51 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr14:27482412-27508460 bp, - strand From Ensembl annotation of GRCm38   26049 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:35309  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ccdc66

Human homologs

Human Homolog		CCDC66, coiled-coil domain containing 66
NCBI Gene ID		285331
neXtProt AC		NX_A2RUB6
Human Chr (Location)		3p14.3; chr3:56591184-56655864 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(7) : Gene trapped(7)
 

Mice homozygous for a null mutation display slowly progressing photoreceptor degeneration.

 
Human Diseases Modeled Using Mouse Ccdc66 (1)    Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (4 annotations)

Process	post-embryonic retina morphogenesis in camera-type eye, retinal rod cell development
Component	cellular_component
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (43)    Tissues (9)    Images (16)
Theiler Stages: 23

Assay Type	Results
RNA in situ	43

cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(10) cDNA(10)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000046753 (Evidence)
Entrez Gene	320234 (Evidence)
DFCI	TC1581129, TC1585329, TC1596483
DoTS	DT.101226199, DT.94129024, DT.94226106, DT.97393935, DT.99838851
NIA Mouse Gene Index	U035342
Consensus CDS Project	CCDS36843.1
International Mouse Knockout Project Status	Ccdc66

Sequences

Length	Strain/Species
genomic	ENSMUSG00000046753	Ensembl Gene Model | MGI Sequence Detail	26049	C57BL/6J
transcript	ENSMUST00000050480	Ensembl | MGI Sequence Detail	2940	Not Applicable
polypeptide	ENSMUSP00000052546	Ensembl | MGI Sequence Detail	935	Not Applicable

All sequences(26) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(71 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000029334	coiled-coil domain-containing protein 66

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:174954 Gerding WM, et al., Ccdc66 null mutation causes retinal degeneration and dysfunction. Hum Mol Genet. 2011 Sep 15;20(18):3620-31
All references(26)