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Pirt
Gene Detail
Symbol

Name
ID
Pirt
phosphoinositide-interacting regulator of transient receptor potential channels
MGI:2443635
Synonyms
A530088H08Rik, Pirt
Feature Type
protein coding gene
Genetic Map
Chromosome 11
40.59 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:66911981-66929876 bp, + strand
From VEGA annotation of GRCm38

  17896 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77645  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 3 chicken; 1 western clawed frog

HCOP human homology predictions: PIRT
Gene Tree: Pirt

Human
homologs
PIRT, phosphoinositide-interacting regulator of transient receptor potential channels
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 644139
neXtProt AC: NX_P0C851

Human Chr (Location): 17p12; chr17:10822475-10838101 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit decreased sensitivity to thermal and capsaicin nociception.
 
Interactions
Pirt interacts with 324 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Component integral component of membrane, membrane
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (97)    Tissues (16)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 97
cDNA source data(12)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000005913 (Evidence)
Ensembl Gene Model ENSMUSG00000048070 (Evidence)
Entrez Gene 193003 (Evidence)
DFCI TC1653309, TC1584577
DoTS DT.101359563, DT.94294447
NIA Mouse Gene Index U012769
Consensus CDS Project CCDS24849.1
International Mouse Phenotyping Consortium Status Pirt
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005913 VEGA Gene Model | MGI Sequence Detail 17896 C57BL/6J ±  kb
transcript OTTMUST00000013166 VEGA | MGI Sequence Detail 4200 Not Applicable 
polypeptide OTTMUSP00000051049 VEGA | MGI Sequence Detail 135 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(84 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000012751 phosphoinositide-interacting protein
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:213013 Kim YS, et al., Central terminal sensitization of TRPV1 by descending serotonergic facilitation modulates chronic pain. Neuron. 2014 Feb 19;81(4):873-87
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory