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Pirt
Gene Detail
 Symbol
Name
ID
Pirt
phosphoinositide-interacting regulator of transient receptor potential channels
MGI:2443635
Synonyms A530088H08Rik, Pirt
Feature Type protein coding gene
Genetic Map
Chromosome 11
40.59 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:66911981-66929876 bp, + strand
From VEGA annotation of GRCm38

  17896 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77645  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 3 chicken; 1 western clawed frog

Gene Tree: Pirt

Human
homologs
Human Homolog PIRT, phosphoinositide-interacting regulator of transient receptor potential channels
NCBI Gene ID 644139
neXtProt AC  NX_P0C851
Human Chr (Location)  17p12; chr17:10822475-10838101 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(3) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit decreased sensitivity to thermal and capsaicin nociception.
 
Interactions
Pirt interacts with 325 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Component integral component of membrane, membrane
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (97)    Tissues (16)    Images (21)
Theiler Stages: 23
Assay TypeResults
RNA in situ 97
cDNA source data(12)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000005913 (Evidence)
Ensembl Gene ModelENSMUSG00000048070 (Evidence)
Entrez Gene193003 (Evidence)
DFCITC1584577, TC1653309
DoTSDT.101359563, DT.94294447
NIA Mouse Gene IndexU012769
Consensus CDS ProjectCCDS24849.1
International Mouse Knockout Project StatusPirt
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005913 VEGA Gene Model | MGI Sequence Detail 17896 C57BL/6J ±  kb
transcript OTTMUST00000013166 VEGA | MGI Sequence Detail 4200 Not Applicable 
polypeptide OTTMUSP00000051049 VEGA | MGI Sequence Detail 135 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(84 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000012751 phosphoinositide-interacting protein
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:174563 Dykes IM, et al., Brn3a and islet1 act epistatically to regulate the gene expression program of sensory differentiation. J Neurosci. 2011 Jul 6;31(27):9789-99
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory