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Pou6f2
Gene Detail
 Symbol
Name
ID
Pou6f2
POU domain, class 6, transcription factor 2
MGI:2443631
Synonyms D130006K24Rik, RPF-1
Feature Type protein coding gene
Genetic Map
Chromosome 13
6.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr13:18121101-18382041 bp, - strand
From VEGA annotation of GRCm38

  260941 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: POU domain class 6 transcription factor 2
Gene Tree: Pou6f2
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are viable, fertile and of normal size with no apparent phenotypic abnormalities.
 
Interactions
Pou6f2 interacts with 455 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process regulation of transcription, DNA-templated, transcription, DNA-templated
Component nucleus
Function DNA binding, sequence-specific DNA binding transcription factor activity
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (130)    Tissues (37)    Images (33)
Theiler Stages: 20, 21, 22, 23, 26, 27
Assay TypeResults
Immunohistochemistry 10
RNA in situ 120
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000029195 (Evidence)
Ensembl Gene ModelENSMUSG00000009734 (Evidence)
Entrez Gene218030 (Evidence)
UniGene352263
DFCITC1586119, TC1589482, TC1590836
DoTSDT.101190637, DT.55115207, DT.91332371
NIA Mouse Gene IndexU034538
International Mouse Knockout Project StatusPou6f2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029195 VEGA Gene Model | MGI Sequence Detail 260941 C57BL/6J ±  kb
transcript OTTMUST00000072394 VEGA | MGI Sequence Detail 5974 Not Applicable 
polypeptide OTTMUSP00000037254 VEGA | MGI Sequence Detail 637 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(2) UniProt(8)
Polymorphisms SNPs within 2kb(1975 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1979)
Protein-related
information
ResourceIDDescription
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR010982 Lambda repressor-like, DNA-binding domain
InterPro IPR013847 POU domain
InterPro IPR000327 POU-specific
Protein Ontology PR:000013047 POU domain, class 6, transcription factor 2
References (Earliest) J:107704 Xiang M, Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors. Dev Biol. 1998 May 15;197(2):155-69
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory