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Gpr149 Gene Detail
Summary
  • Symbol
    Gpr149
  • Name
    G protein-coupled receptor 149
  • Synonyms
    9630018L10Rik, Ieda, PGR10, R35
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443628
    NCBI Gene: 229357
  • Gene Overview
    MyGene.info: GPR149
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr3:62529430-62605442 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 29.97 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    319 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443628
protein coding gene Chr3:62529077-62605442 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027260
protein coding gene Chr3:61503202-61587082 (-)
A/J MGP_AJ_G0027220
protein coding gene Chr3:59722947-59795628 (-)
AKR/J MGP_AKRJ_G0027190
protein coding gene Chr3:60875249-60954468 (-)
BALB/cJ MGP_BALBcJ_G0027233
protein coding gene Chr3:59469000-59544598 (-)
C3H/HeJ MGP_C3HHeJ_G0026976
protein coding gene Chr3:61064910-61149279 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027679
protein coding gene Chr3:63792378-63881831 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025033
protein coding gene Chr3:56224519-56289346 (-)
CAST/EiJ MGP_CASTEiJ_G0026428
protein coding gene Chr3:61253010-61330004 (-)
CBA/J MGP_CBAJ_G0026952
protein coding gene Chr3:65850506-65932851 (-)
DBA/2J MGP_DBA2J_G0027086
protein coding gene Chr3:59104954-59177975 (-)
FVB/NJ MGP_FVBNJ_G0027054
protein coding gene Chr3:57944100-58020461 (-)
LP/J MGP_LPJ_G0027197
protein coding gene Chr3:62363261-62438009 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027071
protein coding gene Chr3:70279590-70360500 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027737
protein coding gene Chr3:60788255-60870144 (-)
PWK/PhJ MGP_PWKPhJ_G0026160
protein coding gene Chr3:58717612-58787150 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025973
protein coding gene Chr3:60315912-60383246 (-)
WSB/EiJ MGP_WSBEiJ_G0026502
protein coding gene Chr3:60929090-61002030 (-)



Homology
more
  • Human Ortholog
    GPR149, G protein-coupled receptor 149
  • Vertebrate Orthologs
    8
  • Human Ortholog
    GPR149, G protein-coupled receptor 149
    Orthology source: HGNC, HomoloGene
  • Synonyms
    IEDA, PGR10, R35
  • Links
    NCBI Gene ID: 344758
    neXtProt AC: NX_Q86SP6
    UniProt: Q86SP6

  • Chr Location
    3q25.2; chr3:154337672-154429715 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Female mice homozygous for a knock-out allele exhibit increased fertility with increased litter size and frequency.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 229357 NCBI Gene Model | MGI Sequence Detail 76013 C57BL/6J ±  kb
transcript NM_001356525 RefSeq | MGI Sequence Detail 4316 C57BL/6  
polypeptide Q3UVY1 UniProt | EBI | MGI Sequence Detail 732 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 2
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/27/2018
MGI 6.13
The Jackson Laboratory