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Plekhm3 Gene Detail
Summary
  • Symbol
    Plekhm3
  • Name
    pleckstrin homology domain containing, family M, member 3
  • Synonyms
    9430067K14Rik, A230102O09Rik, Plekhm1l
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443627
    NCBI Gene: 241075
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:64828279-64995983 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 32.76 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    964 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443627
 protein coding gene Chr1:64825142-64995983 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016099
 protein coding gene Chr1:64971533-65140654 (-)
A/J MGP_AJ_G0016082
 protein coding gene Chr1:62683509-62851716 (-)
AKR/J MGP_AKRJ_G0016039
 protein coding gene Chr1:64444274-64619499 (-)
BALB/cJ MGP_BALBcJ_G0016037
 protein coding gene Chr1:62778907-62950423 (-)
C3H/HeJ MGP_C3HHeJ_G0015869
 protein coding gene Chr1:64713840-64886159 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016490
 protein coding gene Chr1:67484036-67658902 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014211
 protein coding gene Chr1:58740487-58912661 (-)
CAST/EiJ MGP_CASTEiJ_G0015452
 protein coding gene Chr1:63978896-64154101 (-)
CBA/J MGP_CBAJ_G0015841
 protein coding gene Chr1:69680959-69864914 (-)
DBA/2J MGP_DBA2J_G0015942
 protein coding gene Chr1:62086886-62258079 (-)
FVB/NJ MGP_FVBNJ_G0015945
 protein coding gene Chr1:61363340-61532509 (-)
LP/J MGP_LPJ_G0016014
 protein coding gene Chr1:65876282-66049311 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015965
 protein coding gene Chr1:72541018-72718916 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016537
 protein coding gene Chr1:64424545-64594434 (-)
PWK/PhJ MGP_PWKPhJ_G0015239
 protein coding gene Chr1:61480373-61651983 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015018
 protein coding gene Chr1:63906888-64081383 (-)
WSB/EiJ MGP_WSBEiJ_G0015514
 protein coding gene Chr1:64129754-64304160 (-)



Homology
more
  • Human Ortholog
    PLEKHM3, pleckstrin homology domain containing M3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLEKHM3, pleckstrin homology domain containing M3
  • Synonyms
    DAPR, PLEKHM1L
  • Links
    NCBI Gene ID: 389072
    neXtProt AC: NX_Q6ZWE6
    UniProt: Q6ZWE6

  • Chr Location
    2q33.3; chr2:207821288-208025675 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 241075 NCBI Gene Model | MGI Sequence Detail 167705 C57BL/6J ±  kb
transcript NM_001039493 RefSeq | MGI Sequence Detail 8562 Not Specified  
polypeptide Q8BM47 UniProt | EBI | MGI Sequence Detail 761 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 5
Other
Accession IDs
less
MGI:2138249
References
more
  • Summaries
    All 28
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:261835 Virtanen C, et al., Identification and characterization of a novel gene, dapr, involved in skeletal muscle differentiation and protein kinase B signaling. J Biol Chem. 2009 Jan 16;284(3):1636-43
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2022
MGI 6.21 		The Jackson Laboratory