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Tmem91 Gene Detail
Summary
  • Symbol
    Tmem91
  • Name
    transmembrane protein 91
  • Synonyms
    A830041P22Rik, SynDIG3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443589
    NCBI Gene: 320208
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:25368564-25374591 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 13.97 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    283 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443589
 protein coding gene Chr7:25368564-25379011 (-)
129S1/SvImJ ENSMUSG00200041784
 protein coding gene Chr7:15365636-15371664 (-)
A/J ENSMUSG00195052639
 protein coding gene Chr7:17809570-17815598 (-)
AKR/J ENSMUSG00220048124
 protein coding gene Chr7:26574972-26581000 (+)
BALB/cJ ENSMUSG00180052944
 protein coding gene Chr7:15881522-15887550 (-)
C3H/HeJ ENSMUSG00175046027
 protein coding gene Chr7:16925602-16931629 (-)
C57BL/6NJ ENSMUSG00215054775
 protein coding gene Chr7:15285492-15291519 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029377
 protein coding gene Chr7:24883266-24889242 (-)
CAST/EiJ ENSTCUG00005051178
 protein coding gene Chr7:16978920-16985251 (-)
CBA/J ENSMUSG00210052567
 protein coding gene Chr7:16111308-16117337 (-)
DBA/2J ENSMUSG00185054288
 protein coding gene Chr7:19325091-19331117 (-)
FVB/NJ ENSMUSG00205043582
 protein coding gene Chr7:16121967-16127994 (-)
JF1/MsJ ENSUMUG00000025252
 protein coding gene Chr7:23607476-23613534 (-)
LP/J ENSMUSG00230053048
 protein coding gene Chr7:24591774-24597801 (-)
NOD/ShiLtJ ENSMUSG00190044540
 protein coding gene Chr7:15585328-15591349 (-)
NZO/HlLtJ ENSMUSG00225023653
 protein coding gene Chr7:23267068-23273094 (-)
PWK/PhJ ENSLUMG00010046479
 protein coding gene Chr7:15540667-15546918 (-)
SPRET/EiJ ENSMSPG00010049686
 protein coding gene Chr7:15213232-15218969 (-)
WSB/EiJ ENSIUOG00005052466
 protein coding gene Chr7:10080853-10086879 (-)



Homology
more
  • Human Ortholog
    TMEM91, transmembrane protein 91
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM91, transmembrane protein 91
  • Synonyms
    DSPC3, IFITMD6, SynDIG3
  • Links
    NCBI Gene ID: 641649
    UniProt: Q6ZNR0

  • Chr Location
    19q13.2; chr19:41350911-41384083 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061702 Ensembl Gene Model | MGI Sequence Detail 6028 C57BL/6J ±  kb
transcript ENSMUST00000079439 Ensembl | MGI Sequence Detail 877 Not Applicable  
polypeptide ENSMUSP00000078407 Ensembl | MGI Sequence Detail 172 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 1
References
more
  • Summaries
    All 26
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory