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Abat Gene Detail
Summary
  • Symbol
    Abat
  • Name
    4-aminobutyrate aminotransferase
  • Synonyms
    9630038C02Rik, GABA-T
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443582
    NCBI Gene: 268860
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:8513429-8621568 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 4.06 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    349 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443582
protein coding gene Chr16:8513429-8621568 (.)
129S1/SvImJ MGP_129S1SvImJ_G0022493
protein coding gene Chr16:5171768-5285918 (+)
A/J MGP_AJ_G0022455
protein coding gene Chr16:4862018-4976277 (+)
AKR/J MGP_AKRJ_G0022432
protein coding gene Chr16:5144302-5251339 (+)
BALB/cJ MGP_BALBcJ_G0022460
protein coding gene Chr16:5030026-5146914 (+)
C3H/HeJ MGP_C3HHeJ_G0022227
protein coding gene Chr16:5174448-5289590 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022909
protein coding gene Chr16:5314101-5436231 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020430
protein coding gene Chr16:5072389-5177052 (+)
CAST/EiJ MGP_CASTEiJ_G0021753
protein coding gene Chr16:5198476-5309651 (+)
CBA/J MGP_CBAJ_G0022196
protein coding gene Chr16:5521510-5640888 (+)
DBA/2J MGP_DBA2J_G0022327
protein coding gene Chr16:4915837-5023390 (+)
FVB/NJ MGP_FVBNJ_G0022302
protein coding gene Chr16:4897802-5004167 (+)
LP/J MGP_LPJ_G0022395
protein coding gene Chr16:5144918-5261482 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022324
protein coding gene Chr16:5321710-5435000 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022921
protein coding gene Chr16:5089782-5201749 (+)
PWK/PhJ MGP_PWKPhJ_G0021493
protein coding gene Chr16:5082615-5194013 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021324
protein coding gene Chr16:5137954-5257410 (+)
WSB/EiJ MGP_WSBEiJ_G0021802
protein coding gene Chr16:5123442-5239062 (+)



Homology
more
  • Human Ortholog
    ABAT, 4-aminobutyrate aminotransferase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ABAT, 4-aminobutyrate aminotransferase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    GABA-AT, GABAT, NPD009
  • Links
    NCBI Gene ID: 18
    neXtProt AC: NX_P80404
    UniProt: P80404

  • Chr Location
    16p13.2; chr16:8674587-8784575 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ABAT associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 268860 NCBI Gene Model | MGI Sequence Detail 108140 C57BL/6J ±  kb
transcript NM_172961 RefSeq | MGI Sequence Detail 4653 C57BL/6  
polypeptide P61922 UniProt | EBI | MGI Sequence Detail 500 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 124
    cDNA 123
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1930903, MGI:2146392
References
more
  • Summaries
    All 46
    Developmental Gene Expression 6
    Gene Ontology 10
    Phenotypes 7
  • Earliest
    J:15086 Kato K, A collection of cDNA clones with specific expression patterns in mouse brain. Eur J Neurosci. 1990;2(8):704-11
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory