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Mettl20 Gene Detail
Summary
  • Symbol
    Mettl20
  • Name
    methyltransferase like 20
  • Synonyms
    4833442J19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443575
    NCBI Gene: 320204
Location & Maps
more
  • Sequence Map
    Chr6:149139849-149151171 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11323 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ETFBKMT, electron transfer flavoprotein beta subunit lysine methyltransferase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ETFBKMT, electron transfer flavoprotein beta subunit lysine methyltransferase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C12orf72, ETFB-KMT, METTL20
  • Links
    NCBI Gene ID: 254013
    neXtProt AC: NX_Q8IXQ9

  • Chr Location
    12p11.21; chr12:31647160-31669086 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    20
  • Gene trapped
    17
  • Targeted
    3
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026169 VEGA Gene Model | MGI Sequence Detail 11323 C57BL/6J ±  kb
transcript OTTMUST00000064652 VEGA | MGI Sequence Detail 1562 Not Applicable  
polypeptide OTTMUSP00000032137 VEGA | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    32 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000032285 methyltransferase-like protein 20
  • EC
  • InterPro Domains
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 4
Other
Accession IDs
less
MGI:1353587
References
more
  • Summaries
    All 31
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:227369 Rhein VF, et al., Human METTL20 methylates lysine residues adjacent to the recognition loop of the electron transfer flavoprotein in mitochondria. J Biol Chem. 2014 Aug 29;289(35):24640-51

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory