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Wdhd1 Gene Detail
Summary
  • Symbol
    Wdhd1
  • Name
    WD repeat and HMG-box DNA binding protein 1
  • Synonyms
    AND-1, D630024B06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443514
    NCBI Gene: 218973
  • Gene Overview
    MyGene.info: WDHD1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:47240944-47276857 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 24.60 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    247 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443514
protein coding gene Chr14:47240944-47276857 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021219
protein coding gene Chr14:40970111-41011905 (-)
A/J MGP_AJ_G0021166
protein coding gene Chr14:39738422-39773863 (-)
AKR/J MGP_AKRJ_G0021144
protein coding gene Chr14:41274330-41317230 (-)
BALB/cJ MGP_BALBcJ_G0021170
protein coding gene Chr14:39788080-39827227 (-)
C3H/HeJ MGP_C3HHeJ_G0020953
protein coding gene Chr14:41064408-41107816 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021604
protein coding gene Chr14:42717903-42759528 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019163
protein coding gene Chr14:39097985-39133304 (-)
CAST/EiJ MGP_CASTEiJ_G0020478
protein coding gene Chr14:38188618-38228662 (-)
CBA/J MGP_CBAJ_G0020919
protein coding gene Chr14:44073436-44112680 (-)
DBA/2J MGP_DBA2J_G0021042
protein coding gene Chr14:39629983-39667204 (-)
FVB/NJ MGP_FVBNJ_G0021027
protein coding gene Chr14:39371778-39408353 (-)
LP/J MGP_LPJ_G0021112
protein coding gene Chr14:41255217-41292850 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021052
protein coding gene Chr14:43429695-43475232 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021637
protein coding gene Chr14:40829023-40866192 (-)
PWK/PhJ MGP_PWKPhJ_G0020227
protein coding gene Chr14:36505020-36544212 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020051
protein coding gene Chr14:36954558-36990777 (-)
WSB/EiJ MGP_WSBEiJ_G0020534
protein coding gene Chr14:40928086-40963898 (-)



Homology
more
  • Human Ortholog
    WDHD1, WD repeat and HMG-box DNA binding protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WDHD1, WD repeat and HMG-box DNA binding protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AND1, AND-1, CHTF4, CTF4
  • Links
    NCBI Gene ID: 11169
    neXtProt AC: NX_O75717
    UniProt: O75717

  • Chr Location
    14q22.2-q22.3; chr14:54938938-55027105 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 56019
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: WDHD1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic 218973 NCBI Gene Model | MGI Sequence Detail 35914 C57BL/6J ±  kb
transcript NM_001360532 RefSeq | MGI Sequence Detail 4301 C57BL/6  
polypeptide P59328 UniProt | EBI | MGI Sequence Detail 1117 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000017386 WD repeat and HMG-box DNA-binding protein 1
  • InterPro Domains
    IPR024977 Anaphase-promoting complex subunit 4, WD40 domain
    IPR009071 High mobility group box domain
    IPR036910 High mobility group box domain superfamily
    IPR022100 Minichromosome loss protein Mcl1, middle region
    IPR001680 WD40 repeat
    IPR019775 WD40 repeat, conserved site
    IPR017986 WD40-repeat-containing domain
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 71
    cDNA 71

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory