March10 Gene Detail

Summary

• Symbol
  March10
• Name
  membrane-associated ring finger (C3HC4) 10
• Synonyms
  4933417C16Rik, OTTMUSG00000002847, Rnf190

• Feature Type
  protein coding gene
• IDs
  MGI:2443469
  NCBI Gene: 632687
• Alliance
  gene page
• Transcription Start Sites
  4 TSS

Location &
Maps

• Sequence Map
  Chr11:105360798-105456735 bp, - strand
• From Ensembl annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 68.73 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  469 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2443469	protein coding gene	Chr11:105360798-105456862 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0019285	protein coding gene	Chr11:108596036-108689575 (-)
A/J	MGP_AJ_G0019253	protein coding gene	Chr11:103961679-104050919 (-)
AKR/J	MGP_AKRJ_G0019222	protein coding gene	Chr11:107097835-107191819 (-)
BALB/cJ	MGP_BALBcJ_G0019227	protein coding gene	Chr11:104382662-104472762 (-)
C3H/HeJ	MGP_C3HHeJ_G0019036	protein coding gene	Chr11:107391299-107482445 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0019677	protein coding gene	Chr11:111963289-112062385 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017302	protein coding gene	Chr11:101298247-101393062 (-)
CAST/EiJ	MGP_CASTEiJ_G0018589	protein coding gene	Chr11:108434657-108534627 (-)
CBA/J	MGP_CBAJ_G0019005	protein coding gene	Chr11:116601365-116706514 (-)
DBA/2J	MGP_DBA2J_G0019117	protein coding gene	Chr11:103452293-103543529 (-)
FVB/NJ	MGP_FVBNJ_G0019108	protein coding gene	Chr11:102969167-103059126 (-)
LP/J	MGP_LPJ_G0019187	protein coding gene	Chr11:109065390-109157782 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019138	protein coding gene	Chr11:115874536-115970987 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019714	protein coding gene	Chr11:107573984-107666263 (-)
PWK/PhJ	MGP_PWKPhJ_G0018354	protein coding gene	Chr11:104545762-104643332 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0018145	protein coding gene	Chr11:107330001-107428584 (-)
WSB/EiJ	MGP_WSBEiJ_G0018640	protein coding gene	Chr11:107545490-107640181 (-)

Homology

• Human Ortholog
  MARCH10, membrane associated ring-CH-type finger 10

• Vertebrate Orthologs
  7

• Human Ortholog
  MARCH10, membrane associated ring-CH-type finger 10
  Orthology source: HomoloGene, HGNC
• Synonyms
  MARCH-X, RNF190
• Links
  HGNC:26655

  NCBI Gene ID: 162333

  neXtProt AC: NX_Q8NA82

  UniProt: Q8NA82

  
  
• Chr Location
  17q23.2; chr17:62701314-62808381 (-)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 34988
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 macaque, rhesus
  
• HCOP
  human homology predictions: MARCH10
• Gene Tree
  March10
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  3 strains or lines available

Gene Ontology
(GO)
Classifications

• External Resources
  FuncBase

Expression

• cDNA Data
  26

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase march10

Interactions

• March10 interacts with 101 markers (Mir9-1, Mir9-2, Mir9-3, ...) View All

Sequences &
Gene Models

• All Sequences
  50
• RefSeq
  8
• UniProt
  5
• CCDS
  CCDS25540.1, CCDS48955.1
• UniGene
  121570

• Ensembl
  ENSMUSG00000078627 (Evidence)
• NCBI Gene
  632687

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000078627	Ensembl Gene Model | MGI Sequence Detail	95938	C57BL/6J
transcript	ENSMUST00000049995	Ensembl | MGI Sequence Detail	3074	Not Applicable
polypeptide	ENSMUSP00000063198	Ensembl | MGI Sequence Detail	788	Not Applicable

Protein
Information

• UniProt
  5 Sequences
• InterPro Domains
  IPR011016 Zinc finger, RING-CH-type
  IPR013083 Zinc finger, RING/FYVE/PHD-type

Molecular
Reagents

• All nucleic 26

  cDNA 26

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:2144453, MGI:3713496

References

• Summaries
  All 21

  Phenotypes 2
• Earliest
  J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for March10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr3699	Chr11:105456759-105456764 (-)	-27 bp
Tssr111264	Chr11:105456674-105456751 (-)	22 bp
Tssr111263	Chr11:105455299-105455325 (-)	1,423 bp
Tssr111262	Chr11:105455277-105455288 (-)	1,452 bp