Foxj3
Gene Detail

Symbol Name ID

Foxj3 forkhead box J3 MGI:2443432

Synonyms

C330039G02Rik, Fhd6, mKIAA1041

Feature Type

protein coding gene

Genetic Map

Chromosome 4

55.43 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr4:119537004-119629119 bp, + strand From VEGA annotation of GRCm38   92116 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:35243  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Foxj3

Human homologs

Human Homolog		FOXJ3, forkhead box J3
NCBI Gene ID		22887
neXtProt AC		NX_Q9UPW0
Human Chr (Location)		1p34.2; chr1:42642210-42801548 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(31) : Targeted(2) Gene trapped(29)
 

Homozygous null mice have an abnormal skeletal muscle fiber type ratio in males as well as defects in muscle regeneration following injury.

 

Gene Ontology (GO) classifications

All GO classifications: (20 annotations)

Process	embryo development, negative regulation of transcription from RNA polymerase II promoter, ...
Component	nucleus, transcription factor complex
Function	DNA binding, DNA binding, bending, ...

External Resources: FuncBase

Expression

Literature Summary: (9 records)
Data Summary: Results (228)    Tissues (167)    Images (17)
Theiler Stages: 2, 3, 4, 5, 17, 18, 19, 21, 22, 23, 28

Assay Type	Results
RNA in situ	200
In situ reporter (knock in)	3
RT-PCR	25

cDNA source data(76)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(83) cDNA(76) Primer pair(7)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000009437 (Evidence)
Ensembl Gene Model	ENSMUSG00000032998 (Evidence)
Entrez Gene	230700 (Evidence)
UniGene	259227
DFCI	TC1582043, TC1602524, TC1604580, TC1616658, TC1710267
DoTS	DT.101205854, DT.110799348, DT.111028618, DT.60103687, DT.87053927, DT.91598147, DT.94245551
NIA Mouse Gene Index	U004742
Consensus CDS Project	CCDS18585.1
International Mouse Knockout Project Status	Foxj3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000009437	VEGA Gene Model | MGI Sequence Detail	92116	C57BL/6J
transcript	OTTMUST00000021488	VEGA | MGI Sequence Detail	4789	Not Applicable
polypeptide	OTTMUSP00000009818	VEGA | MGI Sequence Detail	623	Not Applicable

All sequences(74) RefSeq(2) UniProt(6)

Polymorphisms

SNPs(357 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001766	Transcription factor, fork head
InterPro	IPR018122	Transcription factor, fork head, conserved site
InterPro	IPR011991	Winged helix-turn-helix DNA-binding domain
Protein Ontology	PR:000007630	forkhead box protein J3

References

(Earliest) J:39656 Farrington SM, et al., Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac. Mech Dev. 1997 Mar;62(2):197-211
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(44)

Other accession IDs

MGI:891992