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Foxj3 Gene Detail
Summary
  • Symbol
    Foxj3
  • Name
    forkhead box J3
  • Synonyms
    C330039G02Rik, Fhd6, mKIAA1041
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443432
    NCBI Gene: 230700
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr4:119537004-119629119 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      92116 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 55.43 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    FOXJ3, forkhead box J3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FOXJ3, forkhead box J3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 22887
    neXtProt AC: NX_Q9UPW0
    UniProt: Q9UPW0

  • Chr Location
    1p34.2; chr1:42176539-42335877 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 2 alleles in 2 genetic backgrounds
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice have an abnormal skeletal muscle fiber type ratio in males as well as defects in muscle regeneration following injury.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000009437 VEGA Gene Model | MGI Sequence Detail 92116 C57BL/6J ±  kb
    transcript OTTMUST00000021488 VEGA | MGI Sequence Detail 4789 Not Applicable  
    polypeptide OTTMUSP00000009818 VEGA | MGI Sequence Detail 623 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      438 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 83
      cDNA 75
      Primer pair 7
      Other 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:891992
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 10
      Gene Ontology 4
      Phenotypes 20
    • Earliest
      J:39656 Farrington SM, et al., Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac. Mech Dev. 1997 Mar;62(2):197-211
    • Latest
      J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    Funding Information
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    last database update
    06/12/2018
    MGI 6.12
    The Jackson Laboratory