About   Help   FAQ
Tmem74 Gene Detail
Summary
  • Symbol
    Tmem74
  • Name
    transmembrane protein 74
  • Synonyms
    B230382K22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443417
    NCBI Gene: 239408
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr15:43866695-43870029 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3335 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 16.82 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TMEM74, transmembrane protein 74
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM74, transmembrane protein 74
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NET36
  • Links
    NCBI Gene ID: 157753
    neXtProt AC: NX_Q96NL1
    UniProt: Q96NL1

  • Chr Location
    8q23.1; chr8:108606850-108787615 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 17684
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TMEM74
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054409 Ensembl Gene Model | MGI Sequence Detail 3335 C57BL/6J ±  kb
transcript ENSMUST00000067469 Ensembl | MGI Sequence Detail 1472 Not Applicable  
polypeptide ENSMUSP00000070748 Ensembl | MGI Sequence Detail 305 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    120 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
Other
Accession IDs
less
MGI:3034807
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:205485 Yu C, et al., CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. Science. 2013 Dec 20;342(6165):1518-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/10/2017
MGI 6.10
The Jackson Laboratory