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Tmem74 Gene Detail
Summary
  • Symbol
    Tmem74
  • Name
    transmembrane protein 74
  • Synonyms
    B230382K22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443417
    NCBI Gene: 239408
Location & Maps
more
  • Sequence Map
    Chr15:43866695-43870029 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3335 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    TMEM74, transmembrane protein 74
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM74, transmembrane protein 74
    Orthology source: HGNC, HomoloGene
  • Synonyms
    NET36
  • Links
    NCBI Gene ID: 157753
    neXtProt AC: NX_Q96NL1

  • Chr Location
    8q23.1; chr8:108783117-108787541 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    2
  • Targeted
    2
  • Genomic Mutations
    2 involving Tmem74
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054409 Ensembl Gene Model | MGI Sequence Detail 3335 C57BL/6J ±  kb
transcript ENSMUST00000067469 Ensembl | MGI Sequence Detail 1472 Not Applicable  
polypeptide ENSMUSP00000070748 Ensembl | MGI Sequence Detail 305 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    120 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000031346 transmembrane protein 74
  • InterPro Domains
    IPR029696 Transmembrane protein 74
    IPR029695 Transmembrane protein 74-like
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
Other
Accession IDs
less
MGI:3034807
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:205485 Yu C, et al., CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. Science. 2013 Dec 20;342(6165):1518-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory