About   Help   FAQ
Relt Gene Detail
Summary
  • Symbol
    Relt
  • Name
    RELT tumor necrosis factor receptor
  • Synonyms
    E430021K24Rik, Tnfrsf19l
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443373
    NCBI Gene: 320100
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:100495054-100512653 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    356 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443373
 protein coding gene Chr7:100495054-100512690 (-)
129S1/SvImJ ENSMUSG00200047926
 protein coding gene Chr7:87324556-87342169 (-)
A/J ENSMUSG00195054226
 protein coding gene Chr7:91830059-91847665 (-)
AKR/J ENSMUSG00220051026
 protein coding gene Chr7:85246693-85264303 (-)
BALB/cJ ENSMUSG00180029008
 protein coding gene Chr7:88503004-88520611 (-)
C3H/HeJ ENSMUSG00175023666
 protein coding gene Chr7:89158482-89176130 (-)
C57BL/6NJ ENSMUSG00215018208
 protein coding gene Chr7:88341334-88358937 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030054
 protein coding gene Chr7:103526268-103543237 (-)
CAST/EiJ ENSTCUG00005051999
 protein coding gene Chr7:91745127-91762765 (-)
CBA/J ENSMUSG00210025009
 protein coding gene Chr7:89012020-89029668 (-)
DBA/2J ENSMUSG00185056762
 protein coding gene Chr7:93333618-93351269 (-)
FVB/NJ ENSMUSG00205020708
 protein coding gene Chr7:89001206-89018815 (-)
JF1/MsJ ENSUMUG00000021985
 protein coding gene Chr7:98239014-98256660 (-)
LP/J ENSMUSG00230038939
 protein coding gene Chr7:99466335-99483937 (-)
NOD/ShiLtJ ENSMUSG00190020391
 protein coding gene Chr7:89281474-89299051 (-)
NZO/HlLtJ ENSMUSG00225048785
 protein coding gene Chr7:97643689-97661303 (-)
PWK/PhJ ENSLUMG00010044292
 protein coding gene Chr7:87489638-87507289 (-)
SPRET/EiJ ENSMSPG00010010588
 protein coding gene Chr7:88730513-88748122 (-)
WSB/EiJ ENSIUOG00005010315
 protein coding gene Chr7:89630503-89648135 (-)



Homology
more
  • Human Ortholog
    RELT, RELT TNF receptor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RELT, RELT TNF receptor
  • Synonyms
    AI3C, TNFRSF19L, TRLT
  • Links
    NCBI Gene ID: 84957
    UniProt: Q969Z4

  • Chr Location
    11q13.4; chr11:73376325-73397474 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Relt mouse models; 1 with human RELT associations

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice with a premature termination codon resulting in a null allele exhibit incisor and molar enamel malformations. Homozygous knockout affects T cell proliferation and reduces tumor growth.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    621
  • Tissues
    15
  • cDNA Data
    19
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000008318 Ensembl Gene Model | MGI Sequence Detail 17600 C57BL/6J ±  kb
    transcript ENSMUST00000008462 Ensembl | MGI Sequence Detail 2851 Not Applicable  
    polypeptide ENSMUSP00000008462 Ensembl | MGI Sequence Detail 436 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 19

      Microarray probesets 3
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 8
      Phenotypes 20
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory