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Gk5 Gene Detail
Summary
  • Symbol
    Gk5
  • Name
    glycerol kinase 5
  • Synonyms
    C330018K18Rik, G630067D24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443336
    NCBI Gene: 235533
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:96001415-96066661 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 50.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    658 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443336
protein coding gene Chr9:96001379-96066680 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035141
protein coding gene Chr9:97281713-97357477 (+)
A/J MGP_AJ_G0035122
protein coding gene Chr9:93895266-93964861 (+)
AKR/J MGP_AKRJ_G0035054
protein coding gene Chr9:96177917-96247232 (+)
BALB/cJ MGP_BALBcJ_G0035115
protein coding gene Chr9:93583757-93653952 (+)
C3H/HeJ MGP_C3HHeJ_G0034825
protein coding gene Chr9:96598825-96670318 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035635
protein coding gene Chr9:100065914-100152149 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032536
protein coding gene Chr9:91722457-91739036 (+)
CAST/EiJ MGP_CASTEiJ_G0034137
protein coding gene Chr9:96345162-96418336 (+)
CBA/J MGP_CBAJ_G0034793
protein coding gene Chr9:103544561-103624708 (+)
DBA/2J MGP_DBA2J_G0034955
protein coding gene Chr9:93422968-93489496 (+)
FVB/NJ MGP_FVBNJ_G0034903
protein coding gene Chr9:92271962-92338907 (+)
LP/J MGP_LPJ_G0035034
protein coding gene Chr9:97556921-97630511 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034942
protein coding gene Chr9:105543422-105614238 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035657
protein coding gene Chr9:96406977-96475767 (+)
PWK/PhJ MGP_PWKPhJ_G0033844
protein coding gene Chr9:93580171-93648812 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033679
protein coding gene Chr9:96421691-96529138 (+)
WSB/EiJ MGP_WSBEiJ_G0034257
protein coding gene Chr9:96277195-96347423 (+)



Homology
more
  • Human Ortholog
    GK5, glycerol kinase 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GK5, glycerol kinase 5
  • Links
    NCBI Gene ID: 256356
    neXtProt AC: NX_Q6ZS86
    UniProt: Q6ZS86

  • Chr Location
    3q23; chr3:142157527-142225592 (-)  GRCh38

  • MGI Vertebrate Homology
    Gk5 stringent orthology
    1 human;1 mouse;1 rat;1 zebrafish
  • HCOP
    vertebrate homology predictions: GK5
  • Protein SuperFamily
  • Gene Tree
    Gk5
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 6 alleles in 6 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for ENU-induced alleles exhibit skin phenotype and alopecia.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041440 Ensembl Gene Model | MGI Sequence Detail 65247 C57BL/6J ±  kb
    transcript ENSMUST00000085217 Ensembl | MGI Sequence Detail 2815 Not Applicable  
    polypeptide ENSMUSP00000082313 Ensembl | MGI Sequence Detail 534 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 37
      cDNA 37

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2444291, MGI:3034778
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:243852 Zhang D, et al., Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5197-E5206

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory