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Tom1l2
Gene Detail
 Symbol
Name
ID
Tom1l2
target of myb1-like 2 (chicken)
MGI:2443306
Synonyms 2900016I08Rik, A730055F12Rik, myb1-like protein 2
Feature Type protein coding gene
Genetic Map
Chromosome 11
37.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:60226715-60352905 bp, - strand
From VEGA annotation of GRCm38

  126191 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:44901  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: target of Myb protein 1
Gene Tree: Tom1l2

Human
homologs
Human Homolog TOM1L2, target of myb1-like 2 (chicken)
NCBI Gene ID 146691
neXtProt AC  NX_Q6ZVM7
Human Chr (Location)  17p11.2; chr17:17843508-17972470 (-)  GRCh38
Alleles
and
phenotypes
All alleles(19) : Gene trapped(19)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a hypomorphic gene trap allele show malocclusion, kyphosis, hydrocephaly, patchy hair, splenomegaly, high B- and T-cell counts, thrombopenia, impaired humoral responses, a high frequency of infections and tumors, renal cysts, skin lesions, freezing behavior and sporadic bleeding.
 
Phenotype Images(1)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process intracellular protein transport, negative regulation of mitosis, ...
Component extracellular vesicular exosome, intracellular
Function clathrin binding, protein kinase binding
External Resources: FuncBase
Expression
cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000005819 (Evidence)
Ensembl Gene ModelENSMUSG00000000538 (Evidence)
Entrez Gene216810 (Evidence)
DFCITC1581146, TC1589601, TC1591846, TC1598674, TC1601241, TC1774156
NIA Mouse Gene IndexU032864
Consensus CDS ProjectCCDS24786.1, CCDS24787.1, CCDS36171.1
International Mouse Knockout Project StatusTom1l2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005819 VEGA Gene Model | MGI Sequence Detail 126191 C57BL/6J ±  kb
transcript OTTMUST00000012898 VEGA | MGI Sequence Detail 4999 Not Applicable 
polypeptide OTTMUSP00000005998 VEGA | MGI Sequence Detail 507 Not Applicable 

For the selected sequences
All sequences(106) RefSeq(22) UniProt(5)
Polymorphisms SNPs within 2kb(1176 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008942 ENTH/VHS
InterPro IPR004152 GAT
InterPro IPR027429 Target of Myb1-like 2
InterPro IPR014645 Target of Myb protein 1
InterPro IPR002014 VHS
InterPro IPR018205 VHS subgroup
Protein Ontology PR:000016531 TOM1-like protein 2
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)
Other
accession IDs
MGI:1920186, MGI:2144430

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory