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Slc35c1
Gene Detail
Symbol

Name
ID
Slc35c1
solute carrier family 35, member C1
MGI:2443301
Synonyms
E430007K15Rik, FUCT1
Feature Type
protein coding gene
Genetic Map
Chromosome 2
51.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:92452764-92460538 bp, - strand
From VEGA annotation of GRCm38

  7775 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41258  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slc35c1

Human
homologs
Human Homolog SLC35C1, solute carrier family 35 (GDP-fucose transporter), member C1
NCBI Gene ID 55343
neXtProt AC  NX_Q96A29
Human Synonyms  CDG2C, FUCT1
Human Chr (Location)  11p11.2; chr11:45804072-45813016 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SLC35C1
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Genomic Mutations involving Slc35c1 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit partial perinatal and postnatal lethality, growth retardation, reduced fertility, leukocytosis, defective lung and primary lymph node development and altered lymphocyte rolling and adhesion. Mortality is increased on an inbred background.
 
Human Diseases Modeled Using Mouse Slc35c1 (1)    Alleles Annotated to Human Diseases(1)   
Interactions
Slc35c1 interacts with 203 markers (Mir1b, Mir15a, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process carbohydrate transport, lipid glycosylation, ...
Component Golgi apparatus, integral component of membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(18)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000014574 (Evidence)
Ensembl Gene ModelENSMUSG00000049922 (Evidence)
Entrez Gene228368 (Evidence)
DFCITC1641258, TC1606978, TC1574526
DoTSDT.101380208, DT.528252, DT.91408065, DT.97340034
Consensus CDS ProjectCCDS16448.1, CCDS16449.1
International Mouse Knockout Project StatusSlc35c1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014574 VEGA Gene Model | MGI Sequence Detail 7775 C57BL/6J ±  kb
transcript OTTMUST00000034544 VEGA | MGI Sequence Detail 3139 Not Applicable 
polypeptide OTTMUSP00000015460 VEGA | MGI Sequence Detail 363 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(4) UniProt(11)
Polymorphisms
SNPs within 2kb(59 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004853 Domain of unknown function DUF250
InterPro IPR013657 UAA transporter
Protein Ontology PR:000015096 GDP-fucose transporter 1
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(30)
Disease annotation references (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory