Slc35c1
Gene Detail

Symbol Name ID

Slc35c1 solute carrier family 35, member C1 MGI:2443301

Synonyms

E430007K15Rik, FUCT1

Feature Type

protein coding gene

Genetic Map

Chromosome 2

51.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr2:92452764-92460538 bp, - strand From VEGA annotation of GRCm38   7775 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:41258  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Slc35c1

Human homologs

Human Homolog		SLC35C1, solute carrier family 35, member C1
NCBI Gene ID		55343
neXtProt AC		NX_Q96A29
Human Synonyms		CDG2C, FUCT1
Human Chr (Location)		11p11.2; chr11:45825623-45834567 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SLC35C1

Alleles and phenotypes

All alleles(3) : Targeted(3)
 

Mice homozygous for a null allele exhibit partial perinatal and postnatal lethality, growth retardation, reduced fertility, leukocytosis, defective lung and primary lymph node development and altered lymphocyte rolling and adhesion. Mortality is increased on an inbred background.

 
Human Diseases Modeled Using Mouse Slc35c1 (1)    Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	carbohydrate transport, lipid glycosylation, ...
Component	Golgi apparatus, integral to membrane, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (6)
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(18) cDNA(18)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000014574 (Evidence)
Ensembl Gene Model	ENSMUSG00000049922 (Evidence)
Entrez Gene	228368 (Evidence)
DFCI	TC1574526, TC1606978, TC1641258
DoTS	DT.101380208, DT.528252, DT.91408065, DT.97340034
Consensus CDS Project	CCDS16448.1, CCDS16449.1
International Mouse Knockout Project Status	Slc35c1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000014574	VEGA Gene Model | MGI Sequence Detail	7775	C57BL/6J
transcript	OTTMUST00000034545	VEGA | MGI Sequence Detail	2668	Not Applicable
polypeptide	OTTMUSP00000015461	VEGA | MGI Sequence Detail	406	Not Applicable

All sequences(57) RefSeq(4) UniProt(6)

Polymorphisms

SNPs(51 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004853	Domain of unknown function DUF250
InterPro	IPR013657	UAA transporter
Protein Ontology	PR:000015096	GDP-fucose transporter 1

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)