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Rab26 Gene Detail
Summary
  • Symbol
    Rab26
  • Name
    RAB26, member RAS oncogene family
  • Synonyms
    A830020M03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443284
    NCBI Gene: 328778
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:24748038-24752696 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    178 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443284
 protein coding gene Chr17:24746215-24753184 (-)
129S1/SvImJ ENSMUSG00200052982
 protein coding gene Chr17:20192706-20199708 (-)
A/J ENSMUSG00195050081
 protein coding gene Chr17:21211541-21218544 (-)
AKR/J ENSMUSG00220025261
 protein coding gene Chr17:20257923-20264924 (-)
BALB/cJ ENSMUSG00180036038
 protein coding gene Chr17:20485184-20492184 (-)
C3H/HeJ ENSMUSG00175043963
 protein coding gene Chr17:20243602-20250602 (-)
C57BL/6NJ ENSMUSG00215050719
 protein coding gene Chr17:20254193-20261163 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021191
 protein coding gene Chr17:20351233-20356293 (-)
CAST/EiJ ENSTCUG00005048897
 protein coding gene Chr17:20824485-20831686 (-)
CBA/J ENSMUSG00210038111
 protein coding gene Chr17:20082433-20089433 (-)
DBA/2J ENSMUSG00185050591
 protein coding gene Chr17:22299871-22306873 (-)
FVB/NJ ENSMUSG00205037383
 protein coding gene Chr17:20551560-20558562 (-)
JF1/MsJ ENSUMUG00000057062
 protein coding gene Chr17:21745989-21752958 (-)
LP/J ENSMUSG00230054589
 protein coding gene Chr17:23697368-23704370 (-)
NOD/ShiLtJ ENSMUSG00190050443
 protein coding gene Chr17:20188613-20195615 (-)
NZO/HlLtJ ENSMUSG00225054065
 protein coding gene Chr17:25619001-25626003 (-)
PWK/PhJ ENSLUMG00010017667
 protein coding gene Chr17:19655345-19662314 (-)
SPRET/EiJ ENSMSPG00010046373
 protein coding gene Chr17:20991536-20998621 (-)
WSB/EiJ ENSIUOG00005049353
 protein coding gene Chr17:20937520-20944524 (-)



Homology
more
  • Human Ortholog
    RAB26, RAB26, member RAS oncogene family
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB26, RAB26, member RAS oncogene family
  • Synonyms
    V46133
  • Links
    NCBI Gene ID: 25837
    UniProt: Q9ULW5

  • Chr Location
    16p13.3; chr16:2140803-2154165 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice show aggravated LPS-induced acute lung injury.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    48
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 328778 NCBI Gene Model | MGI Sequence Detail 4659 C57BL/6J ±  kb
transcript NM_177375 RefSeq | MGI Sequence Detail 1399 C57BL/6  
polypeptide Q504M8 UniProt | EBI | MGI Sequence Detail 260 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 43
    Gene Ontology 11
    Phenotypes 7
  • Earliest
    J:75312 Kuroda TS, et al., The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. J Biol Chem. 2002 Mar 15;277(11):9212-8
  • Latest
    J:370384 Ren Y, et al., Deficiency of Rab26 causes behavioral defects in mice through impaired trafficking of serotonin (5-HT) transporter. iScience. 2025 Jul 18;28(7):112931
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory