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Agfg2 Gene Detail
Summary
  • Symbol
    Agfg2
  • Name
    ArfGAP with FG repeats 2
  • Synonyms
    A630095P14Rik, Hrbl, MGC:61203, MGC:7148
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443267
    NCBI Gene: 231801
  • Gene Overview
    MyGene.info: AGFG2
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:137650463-137684726 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 76.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    183 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443267
protein coding gene Chr5:137650463-137684806 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030240
protein coding gene Chr5:142428662-142464979 (-)
A/J MGP_AJ_G0030208
protein coding gene Chr5:136216011-136254127 (-)
AKR/J MGP_AKRJ_G0030141
protein coding gene Chr5:140644731-140679621 (-)
BALB/cJ MGP_BALBcJ_G0030218
protein coding gene Chr5:137592638-137626543 (-)
C3H/HeJ MGP_C3HHeJ_G0029934
protein coding gene Chr5:141297522-141342580 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030670
protein coding gene Chr5:147688554-147730042 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027888
protein coding gene Chr5:130459504-130493567 (-)
CAST/EiJ MGP_CASTEiJ_G0029344
protein coding gene Chr5:140698777-140737646 (-)
CBA/J MGP_CBAJ_G0029904
protein coding gene Chr5:153566201-153612281 (-)
DBA/2J MGP_DBA2J_G0030055
protein coding gene Chr5:136117852-136152399 (-)
FVB/NJ MGP_FVBNJ_G0030010
protein coding gene Chr5:135325394-135360879 (-)
LP/J MGP_LPJ_G0030144
protein coding gene Chr5:142901972-142943544 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030042
protein coding gene Chr5:156378996-156415371 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030711
protein coding gene Chr5:140495756-140534858 (-)
PWK/PhJ MGP_PWKPhJ_G0029057
protein coding gene Chr5:135208688-135247949 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028893
protein coding gene Chr5:138066871-138102121 (-)
WSB/EiJ MGP_WSBEiJ_G0029417
protein coding gene Chr5:141227683-141266772 (-)



Homology
more
  • Human Ortholog
    AGFG2, ArfGAP with FG repeats 2
  • Vertebrate Orthologs
    5
  • Human Ortholog
    AGFG2, ArfGAP with FG repeats 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HRBL, RABR
  • Links
    NCBI Gene ID: 3268
    neXtProt AC: NX_O95081
    UniProt: O95081

  • Chr Location
    7q22.1; chr7:100539211-100568220 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029722 Ensembl Gene Model | MGI Sequence Detail 34264 C57BL/6J ±  kb
transcript ENSMUST00000100544 Ensembl | MGI Sequence Detail 2858 Not Applicable  
polypeptide ENSMUSP00000098112 Ensembl | MGI Sequence Detail 490 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR038508 ArfGAP domain superfamily
    IPR037278 ARFGAP/RecO-like zinc finger
    IPR001164 Arf GTPase activating protein
Molecular
Reagents
less
  • All nucleic 43
    cDNA 43

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:113837 Coda L, et al., Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization. J Biol Chem. 1998 Jan 30;273(5):3003-12
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory