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Exph5 Gene Detail
Summary
  • Symbol
    Exph5
  • Name
    exophilin 5
  • Synonyms
    AC079869.22gm5, B130009M24Rik, slac2-b, Slac2b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443248
    NCBI Gene: 320051
Location & Maps
more
  • Sequence Map
    Chr9:53301670-53377514 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      75845 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    EXPH5, exophilin 5
  • Vertebrate Orthologs
    7
  • Human Ortholog
    EXPH5, exophilin 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SLAC2B, SLAC2-B
  • Links
    NCBI Gene ID: 23086
    neXtProt AC: NX_Q8NEV8

  • Chr Location
    11q22.3; chr11:108505431-108593765 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human EXPH5 associations

Human Disease Mouse Models
       Epidermolysis Bullosa, Nonspecific, Autosomal Recessive; EBNS   OMIM: 615028
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031816 VEGA Gene Model | MGI Sequence Detail 75845 C57BL/6J ±  kb
transcript OTTMUST00000078893 VEGA | MGI Sequence Detail 5957 Not Applicable  
polypeptide OTTMUSP00000042006 VEGA | MGI Sequence Detail 1960 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    188 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 1
    cDNA 14

    Microarray probesets 2
Other
Accession IDs
less
MGI:2158493
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:75312 Kuroda TS, et al., The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. J Biol Chem. 2002 Mar 15;277(11):9212-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory