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Ndufs1
Gene Detail
Symbol

Name
ID
Ndufs1
NADH dehydrogenase (ubiquinone) Fe-S protein 1
MGI:2443241
Synonyms
5830412M15Rik, 9930026A05Rik, MGC:19199, MGC:7850
Feature Type
protein coding gene
Genetic Map
Chromosome 1
32.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr1:63143596-63176833 bp, - strand
From VEGA annotation of GRCm38

  33238 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3670  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NDUFS1
Protein SuperFamily: NADH dehydrogenase (ubiquinone) chain 11
Gene Tree: Ndufs1

Human
homologs
NDUFS1, NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4719
neXtProt AC: NX_P28331

Human Synonyms: CI-75k, CI-75Kd, PRO1304

Human Chr (Location): 2q33-q34; chr2:206123079-206159519 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NDUFS1

Mutations,
alleles, and
phenotypes
All mutations/alleles(40) : Gene trapped(37) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ndufs1 interacts with 61 markers (Mir1b, Mir19a, Mir29b-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (294)    Tissues (121)    Images (39)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 294
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ndufs1 ; ZFIN ndufs1    NEW 
Molecular
reagents
All nucleic(16) cDNA(15) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000002613 (Evidence)
Ensembl Gene Model ENSMUSG00000025968 (Evidence)
Entrez Gene 227197 (Evidence)
DFCI TC1604077, TC1571978, TC1617209, TC1610588, TC1698878
DoTS DT.101225518, DT.497069, DT.97363356, DT.91441875, DT.55194182, DT.97363364, DT.99868375, DT.97365497
NIA Mouse Gene Index U021392
EC 1.6.5.3, 1.6.99.3
Consensus CDS Project CCDS14996.1
International Mouse Phenotyping Consortium Status Ndufs1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002613 VEGA Gene Model | MGI Sequence Detail 33238 C57BL/6J ±  kb
transcript OTTMUST00000005068 VEGA | MGI Sequence Detail 2661 Not Applicable 
polypeptide OTTMUSP00000002422 VEGA | MGI Sequence Detail 727 Not Applicable 

For the selected sequences
All sequences(103) RefSeq(10) UniProt(9)
Polymorphisms
SNPs within 2kb(79 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001041 2Fe-2S ferredoxin-type domain
InterPro IPR012675 Beta-grasp domain
InterPro IPR006656 Molybdopterin oxidoreductase
InterPro IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain
InterPro IPR015405 NADH-quinone oxidoreductase, chain G, C-terminal
InterPro IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site
InterPro IPR010228 NADH:ubiquinone oxidoreductase, subunit G
InterPro IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding
Protein Ontology PR:000011096 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:172853 Kohr MJ, et al., Characterization of potential S-nitrosylation sites in the myocardium. Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1327-35
All references(44)
Other
accession IDs
MGI:1922005

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory