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Wdr19
Gene Detail
 Symbol
Name
ID
Wdr19
WD repeat domain 19
MGI:2443231
Synonyms C330027H04Rik, D330023L08Rik, DYF2, Ift144
Feature Type protein coding gene
Genetic Map
Chromosome 5
33.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:65199696-65260415 bp, + strand
From NCBI annotation of GRCm38

  60720 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11842  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Wdr19

Human
homologs
Human Homolog WDR19, WD repeat domain 19
NCBI Gene ID 57728
neXtProt AC  NX_Q8NEZ3
Human Synonyms  ATD5, CED4, DYF-2, IFT144, NPHP13, ORF26, Oseg6, PWDMP, SRTD5
Human Chr (Location)  4p14; chr4:39182404-39285810 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human WDR19
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Chemically induced (ENU)(2) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E10.
 
Interactions
Wdr19 interacts with 109 markers (Mir7-2, Mir7b, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (35 annotations)
Process cell morphogenesis, cell projection organization, ...
Component cell, cell projection, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (15)    Tissues (15)   
Theiler Stages: 28
Assay TypeResults
Northern blot 15
cDNA source data(44)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(45) cDNA(44) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000037890 (Evidence)
Entrez Gene213081 (Evidence)
UniGene127550
DFCITC1581475, TC1592087, TC1592864, TC1607208, TC1627315, TC1702178
DoTSDT.101244108, DT.101294951, DT.101333778, DT.101367695, DT.101707841, DT.103583465, DT.482730, DT.91329410, DT.94137483
NIA Mouse Gene IndexU005625
Consensus CDS ProjectCCDS51509.1
International Mouse Knockout Project StatusWdr19
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 213081 NCBI Gene Model | MGI Sequence Detail 60720 C57BL/6J ±  kb
transcript NM_153391 RefSeq | MGI Sequence Detail 4403 Not Specified 
polypeptide Q3UGF1 UniProt | EBI | MGI Sequence Detail 1341 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(317 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011990 Tetratricopeptide-like helical
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000032482 WD repeat-containing protein 19
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:193954 Wei Q, et al., The BBSome controls IFT assembly and turnaround in cilia. Nat Cell Biol. 2012 Sep;14(9):950-7
All references(37)
Other
accession IDs
MGI:1924484

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory