Tmem260 Gene Detail

Summary

• Symbol
  Tmem260
• Name
  transmembrane protein 260
• Synonyms
  6720456H20Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2443219
  NCBI Gene: 218989
• Gene Overview
  MyGene.info: TMEM260
• Alliance
  gene page

Location & Maps

• Sequence Map
  Chr14:48446128-48515135 bp, + strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    69008 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 25.06 cM
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  TMEM260, transmembrane protein 260

• Vertebrate Orthologs
  10

• Human Ortholog
  TMEM260, transmembrane protein 260
  Orthology source: HomoloGene, HGNC
• Synonyms
  C14orf101, SHDRA
• Links
  HGNC:20185

  NCBI Gene ID: 54916

  neXtProt AC: NX_Q9NX78

  UniProt: Q9NX78

  
  
• Chr Location
  14q22.3; chr14:56579791-56660629 (+)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 49506
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: TMEM260
• Gene Tree
  Tmem260
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  1
• Gene trapped
  1
• Targeted
  3
• Genomic Mutations
  1 involving Tmem260
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  33 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  1

• External Resources
  FuncBase

Expression

• cDNA Data
  53

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Tmem260 interacts with 446 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

Sequences &
Gene Models

• All Sequences
  55
• RefSeq
  13
• UniProt
  2
• CCDS
  CCDS26993.2, CCDS79318.1
• UniGene
  85211

• VEGA
  OTTMUSG00000025627 (Evidence)
• Ensembl
  ENSMUSG00000036339 (Evidence)
• NCBI Gene
  218989

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000025627	VEGA Gene Model | MGI Sequence Detail	69008	C57BL/6J
transcript	OTTMUST00000063042	VEGA | MGI Sequence Detail	5164	Not Applicable
polypeptide	OTTMUSP00000031147	VEGA | MGI Sequence Detail	703	Not Applicable

Polymorphisms

• SNPs within 2kb
  741 from dbSNP Build 142

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR021280 Protein of unknown function DUF2723

Molecular
Reagents

• All nucleic 53

  cDNA 53

  
  

  Microarray probesets 2

References

• Summaries
  All 23

  Gene Ontology 1

  Phenotypes 5
• Earliest
  J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42