Tmem260 Gene Detail

Summary

• Symbol
  Tmem260
• Name
  transmembrane protein 260
• Synonyms
  6720456H20Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2443219
  NCBI Gene: 218989
• Gene Overview
  MyGene.info: TMEM260
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr14:48446123-48520708 bp, + strand
• From NCBI annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 25.06 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  750 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2443219	protein coding gene	Chr14:48446123-48524246 (.)
129S1/SvImJ	MGP_129S1SvImJ_G0021226	protein coding gene	Chr14:42288618-42362161 (+)
A/J	MGP_AJ_G0021175	protein coding gene	Chr14:40969527-41039295 (+)
AKR/J	MGP_AKRJ_G0021153	protein coding gene	Chr14:42572125-42640447 (+)
BALB/cJ	MGP_BALBcJ_G0021178	protein coding gene	Chr14:41026118-41095912 (+)
C3H/HeJ	MGP_C3HHeJ_G0020961	protein coding gene	Chr14:42355732-42426543 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021613	protein coding gene	Chr14:44048746-44117236 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019172	protein coding gene	Chr14:40301896-40369871 (+)
CAST/EiJ	MGP_CASTEiJ_G0020487	protein coding gene	Chr14:39496058-39562970 (+)
CBA/J	MGP_CBAJ_G0020928	protein coding gene	Chr14:45466791-45539003 (+)
DBA/2J	MGP_DBA2J_G0021051	protein coding gene	Chr14:40854926-40923456 (+)
FVB/NJ	MGP_FVBNJ_G0021036	protein coding gene	Chr14:40599681-40668406 (+)
LP/J	MGP_LPJ_G0021120	protein coding gene	Chr14:42538036-42608207 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021061	protein coding gene	Chr14:44783315-44854261 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021646	protein coding gene	Chr14:42113647-42183075 (+)
PWK/PhJ	MGP_PWKPhJ_G0020235	protein coding gene	Chr14:37744453-37816096 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0020060	protein coding gene	Chr14:38246393-38314767 (+)
WSB/EiJ	MGP_WSBEiJ_G0020543	protein coding gene	Chr14:42214278-42285560 (+)

Homology

• Human Ortholog
  TMEM260, transmembrane protein 260

• Vertebrate Orthologs
  10

• Human Ortholog
  TMEM260, transmembrane protein 260
  Orthology source: HomoloGene, HGNC
• Synonyms
  C14orf101, SHDRA
• Links
  HGNC:20185

  NCBI Gene ID: 54916

  neXtProt AC: NX_Q9NX78

  UniProt: Q9NX78

  
  
• Chr Location
  14q22.3; chr14:56579791-56660629 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 49506
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: TMEM260
• Gene Tree
  Tmem260
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotypes from 1 allele in 1 genetic background
  7 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  1
• Gene trapped
  1
• Targeted
  3
• Genomic Mutations
  1 involving Tmem260
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  34 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  1

• External Resources
  FuncBase

Expression

• cDNA Data
  54

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase tmem260

Interactions

• Tmem260 interacts with 446 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

Sequences &
Gene Models

• All Sequences
  79
• RefSeq
  13
• UniProt
  6
• CCDS
  CCDS26993.2, CCDS79318.1
• UniGene
  85211

• Ensembl
  ENSMUSG00000036339 (Evidence)
• NCBI Gene
  218989

Representative Sequences			Length	Strain/Species
genomic	218989	NCBI Gene Model | MGI Sequence Detail	74586	C57BL/6J
transcript	NM_001310584	RefSeq | MGI Sequence Detail	5401	Not Specified
polypeptide	Q8BMD6	UniProt | EBI | MGI Sequence Detail	703	Not Applicable

Protein
Information

• UniProt
  6 Sequences
• InterPro Domains
  IPR021280 Protein of unknown function DUF2723

Molecular
Reagents

• All nucleic 54

  cDNA 54

  
  

  Microarray probesets 2

References

• Summaries
  All 25

  Gene Ontology 1

  Phenotypes 7
• Earliest
  J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Tmem260:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr125341	Chr14:48446340-48446429 (+)	262 bp