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Dlx6os1 Gene Detail
Summary
  • Symbol
    Dlx6os1
  • Name
    distal-less homeobox 6, opposite strand 1
  • Synonyms
    A230055N17Rik, Dlx6as1, Dlx6os1, Evf1, Evf-1, Evf1/2, Evf2, Evf-2, mEvf-1, Shhrs
  • Feature Type
    antisense lncRNA gene
  • IDs
    MGI:2443217
    NCBI Gene: 320038
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:6820546-6869533 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 2.68 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    266 from dbSNP Build 142
  • Strain Annotations
    34
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443217
antisense lncRNA gene Chr6:6820189-6871633 (-)
129S1/SvImJ MGP_129S1SvImJ_G0004230
antisense lncRNA gene Chr6:3735930-3791804 (-)
129S1/SvImJ MGP_129S1SvImJ_G0009756
unclassified non-coding RNA gene Chr6:3791700-3791845 (-)
A/J MGP_AJ_G0009742
unclassified non-coding RNA gene Chr6:3642787-3642932 (-)
A/J MGP_AJ_G0004208
antisense lncRNA gene Chr6:3591318-3642891 (-)
AKR/J MGP_AKRJ_G0004189
antisense lncRNA gene Chr6:3694125-3748897 (-)
AKR/J MGP_AKRJ_G0009726
unclassified non-coding RNA gene Chr6:3748793-3748938 (-)
BALB/cJ MGP_BALBcJ_G0004195
antisense lncRNA gene Chr6:3542852-3596044 (-)
BALB/cJ MGP_BALBcJ_G0009725
unclassified non-coding RNA gene Chr6:3595940-3596085 (-)
C3H/HeJ MGP_C3HHeJ_G0004143
antisense lncRNA gene Chr6:3630522-3686399 (-)
C3H/HeJ MGP_C3HHeJ_G0009658
unclassified non-coding RNA gene Chr6:3686295-3686440 (-)
C57BL/6NJ MGP_C57BL6NJ_G0004344
antisense lncRNA gene Chr6:3821772-3879441 (-)
C57BL/6NJ MGP_C57BL6NJ_G0009968
unclassified non-coding RNA gene Chr6:3879337-3879482 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0003817
antisense lncRNA gene Chr6:3213335-3253235 (-)
CAST/EiJ MGP_CASTEiJ_G0009478
unclassified non-coding RNA gene Chr6:3705736-3705881 (-)
CAST/EiJ MGP_CASTEiJ_G0004105
antisense lncRNA gene Chr6:3649742-3705840 (-)
CBA/J MGP_CBAJ_G0009631
unclassified non-coding RNA gene Chr6:4020837-4020982 (-)
CBA/J MGP_CBAJ_G0004137
antisense lncRNA gene Chr6:3968613-4020941 (-)
DBA/2J MGP_DBA2J_G0004153
antisense lncRNA gene Chr6:3531115-3583052 (-)
DBA/2J MGP_DBA2J_G0009659
unclassified non-coding RNA gene Chr6:3582948-3583093 (-)
FVB/NJ MGP_FVBNJ_G0009675
unclassified non-coding RNA gene Chr6:3568658-3568803 (-)
FVB/NJ MGP_FVBNJ_G0004169
antisense lncRNA gene Chr6:3515735-3568762 (-)
LP/J MGP_LPJ_G0009752
unclassified non-coding RNA gene Chr6:3735925-3736070 (-)
LP/J MGP_LPJ_G0004231
antisense lncRNA gene Chr6:3683056-3736029 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0009644
unclassified non-coding RNA gene Chr6:4054267-4054412 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0004159
antisense lncRNA gene Chr6:3997044-4054371 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0009941
unclassified non-coding RNA gene Chr6:3687451-3687596 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0004341
antisense lncRNA gene Chr6:3630448-3687555 (-)
PWK/PhJ MGP_PWKPhJ_G0009399
unclassified non-coding RNA gene Chr6:3522327-3522472 (-)
PWK/PhJ MGP_PWKPhJ_G0004058
antisense lncRNA gene Chr6:3469705-3522431 (-)
SPRET/EiJ MGP_SPRETEiJ_G0004002
antisense lncRNA gene Chr6:3689264-3740256 (-)
SPRET/EiJ MGP_SPRETEiJ_G0009236
unclassified non-coding RNA gene Chr6:3740152-3740297 (-)
WSB/EiJ MGP_WSBEiJ_G0009578
unclassified non-coding RNA gene Chr6:3683689-3683834 (-)
WSB/EiJ MGP_WSBEiJ_G0004141
antisense lncRNA gene Chr6:3629000-3683793 (-)



Homology
more
  • Human Ortholog
    DLX6-AS1, DLX6 antisense RNA 1
  • Human Ortholog
    DLX6-AS1, DLX6 antisense RNA 1
    Orthology source: HGNC
  • Synonyms
    DLX6AS, DLX6-AS, Evf-2, NCRNA00212
  • Links
    NCBI Gene ID: 285987

  • Chr Location
    7q21.3; chr7:96968515-97014065 (-)  GRCh38.p7

  • HCOP
    human homology predictions: DLX6-AS1
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-in allele exhibit temporary loss of GABAergic interneurons and decreased inhibitory postsynaptic currents.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    • UniGene
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 320038 NCBI Gene Model | MGI Sequence Detail 48988 C57BL/6J ±  kb
    transcript NR_015388 RefSeq | MGI Sequence Detail 4266 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 24
      cDNA 20
      Primer pair 3
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 18
      Diseases 1
      Gene Ontology 1
      Phenotypes 11
    • Earliest
      J:76480 Robledo RF, et al., The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 2002 May 1;16(9):1089-101
    • Latest
      J:265948 Cajigas I, et al., The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain. Mol Cell. 2018 Sep 20;71(6):956-972.e9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    Funding Information
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    last database update
    06/11/2019
    MGI 6.14
    The Jackson Laboratory