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Zfp384 Gene Detail
Summary
  • Symbol
    Zfp384
  • Name
    zinc finger protein 384
  • Synonyms
    C130073D16Rik, Ciz, Nmp4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443203
    NCBI Gene: 269800
  • Gene Overview
    MyGene.info: ZNF384
Location & Maps
more
  • Sequence Map
    Chr6:125009145-125037865 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      28721 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 59.17 cM, cytoband F1
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    ZNF384, zinc finger protein 384
  • Vertebrate Orthologs
    12
  • Human Ortholog
    ZNF384, zinc finger protein 384
    Orthology source: HomoloGene
  • Synonyms
    CAGH1, CAGH1A, CIZ, ERDA2, NMP4, NP, TNRC1
  • Links
    NCBI Gene ID: 171017
    neXtProt AC: NX_Q8TF68

  • Chr Location
    chr12:6666477-6689572 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    17
  • Gene trapped
    13
  • Targeted
    4
  • Incidental Mutations
Homozygous mice are small and males have a small testis. Some males develop infertility and exhibit variable degrees of spermatogenic cell degeneration within the seminiferous tubules and increased apoptosis of spermatogenic cells.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022893 VEGA Gene Model | MGI Sequence Detail 28721 C57BL/6J ±  kb
transcript OTTMUST00000055064 VEGA | MGI Sequence Detail 3072 Not Applicable  
polypeptide OTTMUSP00000026315 VEGA | MGI Sequence Detail 584 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    118 from dbSNP Build 142
Protein
Information
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  • UniProt
    12 Sequences
  • InterPro Domains
    IPR007087 Zinc finger, C2H2
    IPR015880 Zinc finger, C2H2-like
    IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Molecular
Reagents
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  • All nucleic 40
    Genomic 1
    cDNA 37
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
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MGI:1927291, MGI:2141735
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:75532 Alvarez MB, et al., Assignment of Nmp4 to mouse chromosome 6 band F1 flanked by D6Mit134 and D6Mit255 using radiation hybrid mapping and fluorescence in situ hybridization. Cytogenet Cell Genet. 2001;94(3-4):244-5
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory