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Slitrk6
Gene Detail
Symbol

Name
ID
Slitrk6
SLIT and NTRK-like family, member 6
MGI:2443198
Synonyms
4832410J21Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 14
57.20 cM, cytoband E3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:110748578-110755149 bp, - strand
From Ensembl annotation of GRCm38

  6572 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12986  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLITRK6
Gene Tree: Slitrk6

Human
homologs
SLITRK6, SLIT and NTRK-like family, member 6
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 84189
neXtProt AC: NX_Q9H5Y7

Human Synonyms: DFNMYP

Human Chr (Location): 13q31.1; chr13:85792787-85799348 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SLITRK6

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous deficient mice show pronounced reduction in cochlear innervation. Innervation to the posterior crista is variably impaired and a there is a loss of neurons in the spiral and vestibular ganglia.
 
Interactions
Slitrk6 interacts with 286 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process adult locomotory behavior, auditory behavior, ...
Component cell periphery, cell surface, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (189)    Tissues (68)    Images (46)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 158
Northern blot 29
RT-PCR 2
cDNA source data(17)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase slitrk6    NEW 
Molecular
reagents
All nucleic(20) cDNA(17) Primer pair(1) Other(2)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000045871 (Evidence)
Entrez Gene 239250 (Evidence)
UniGene 49728
DFCI TC1584371
DoTS DT.91388972, DT.94167386
NIA Mouse Gene Index U035906
Consensus CDS Project CCDS27326.1
International Mouse Phenotyping Consortium Status Slitrk6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045871 Ensembl Gene Model | MGI Sequence Detail 6572 C57BL/6J ±  kb
transcript ENSMUST00000078386 Ensembl | MGI Sequence Detail 4242 Not Applicable 
polypeptide ENSMUSP00000077492 Ensembl | MGI Sequence Detail 840 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(79 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
InterPro IPR001611 Leucine-rich repeat
InterPro IPR003591 Leucine-rich repeat, typical subtype
Protein Ontology PR:000015242 SLIT and NTRK-like protein 6
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:211830 Um JW, et al., Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Cell Rep. 2014 Mar 27;6(6):1096-109
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory