Sidt1 MGI Mouse Gene Detail - MGI:2443155 - SID1 transmembrane family, member 1

Symbol

Sidt1
Name

SID1 transmembrane family, member 1
Synonyms

B830021E24Rik

Feature Type

protein coding gene
IDs

MGI:2443155
NCBI Gene: 320007
Alliance

gene page
Transcription Start Sites

8 TSS

Sequence Map

Chr16:44060543-44153559 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 16, 28.57 cM
Mapping Data

2 experiments

SNPs within 2kb

630 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2443155	protein coding gene	Chr16:44060540-44153575 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0022837	protein coding gene	Chr16:42983950-43082543 (-)
A/J	MGP_AJ_G0022802	protein coding gene	Chr16:41042510-41139269 (-)
AKR/J	MGP_AKRJ_G0022774	protein coding gene	Chr16:42353622-42455173 (-)
BALB/cJ	MGP_BALBcJ_G0022803	protein coding gene	Chr16:41028639-41124919 (-)
C3H/HeJ	MGP_C3HHeJ_G0022567	protein coding gene	Chr16:42551903-42652955 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0023250	protein coding gene	Chr16:43970346-44067888 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020765	protein coding gene	Chr16:41091259-41182295 (-)
CAST/EiJ	MGP_CASTEiJ_G0022093	protein coding gene	Chr16:42753528-42853739 (-)
CBA/J	MGP_CBAJ_G0022538	protein coding gene	Chr16:45823556-45934153 (-)
DBA/2J	MGP_DBA2J_G0022670	protein coding gene	Chr16:40785458-40877811 (-)
FVB/NJ	MGP_FVBNJ_G0022645	protein coding gene	Chr16:40742678-40835769 (-)
LP/J	MGP_LPJ_G0022738	protein coding gene	Chr16:42693136-42794769 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022664	protein coding gene	Chr16:45218341-45319443 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0023265	protein coding gene	Chr16:42383890-42485583 (-)
PWK/PhJ	MGP_PWKPhJ_G0021833	protein coding gene	Chr16:41171014-41266042 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0021664	protein coding gene	Chr16:42280582-42381503 (-)
WSB/EiJ	MGP_WSBEiJ_G0022137	protein coding gene	Chr16:42476125-42578290 (-)

Human Ortholog

SIDT1, SID1 transmembrane family member 1

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SIDT1, SID1 transmembrane family member 1
Synonyms

SID1, SID-1
Links

HGNC:25967

NCBI Gene ID: 54847

neXtProt AC: NX_Q9NXL6

UniProt: Q9NXL6
Chr Location

3q13.2; chr3:113531774-113629579 (+) GRCh38.p7

Alliance of Genome Resources

Sidt1 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: SIDT1
Gene Tree

Sidt1

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

4
Endonuclease-mediated

1
Targeted

3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

27 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

11
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell death	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	nucleic acid-templated transcription	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

678
Tissues

6
cDNA Data

39
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase sidt1

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Sidt1 interacts with 216 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

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All Sequences

58
RefSeq

10
UniProt

6
CCDS

CCDS28185.1, CCDS49853.1

Ensembl

ENSMUSG00000022696 (Evidence)
NCBI Gene

320007

			Length	Strain/Species	Flank
genomic	ENSMUSG00000022696	Ensembl Gene Model \| MGI Sequence Detail	93017	C57BL/6J	± kb
transcript	ENSMUST00000047446	Ensembl \| MGI Sequence Detail	4279	Not Applicable
polypeptide	ENSMUSP00000038433	Ensembl \| MGI Sequence Detail	832	Not Applicable

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UniProt

6 Sequences
Protein Ontology

PR:000030912 SID1 transmembrane family member 1

(term hierarchy)
InterPro Domains

IPR025958 SID1 transmembrane family

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All nucleic 39

cDNA 39

Microarray probesets 3

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MGI:2146609

Summaries

All 33

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 10
Earliest

J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
Latest

J:320013 Morell M, et al., SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model. EBioMedicine. 2022 Jan 19;76:103808

TSS for Sidt1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr141187	Chr16:44153498-44153520 (-)	50 bp
Tssr141186	Chr16:44153373-44153389 (-)	178 bp
Tssr141185	Chr16:44153288-44153367 (-)	231 bp
Tssr141184	Chr16:44153205-44153231 (-)	341 bp
Tssr141183	Chr16:44153066-44153077 (-)	487 bp
Tssr141182	Chr16:44153032-44153049 (-)	518 bp
Tssr141181	Chr16:44152988-44153031 (-)	549 bp
Tssr141180	Chr16:44083215-44083225 (-)	70,339 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 06/28/2022 MGI 6.20