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Ppwd1 Gene Detail
Summary
  • Symbol
    Ppwd1
  • Name
    peptidylprolyl isomerase domain and WD repeat containing 1
  • Synonyms
    4632422M10Rik, A330090G21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443069
    NCBI Gene: 238831
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:104205124-104228843 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 56.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    315 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443069
 protein coding gene Chr13:104203594-104228844 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020906
 protein coding gene Chr13:106295799-106323644 (-)
A/J MGP_AJ_G0020857
 protein coding gene Chr13:102160266-102183562 (-)
AKR/J MGP_AKRJ_G0020832
 protein coding gene Chr13:105270592-105295755 (-)
BALB/cJ MGP_BALBcJ_G0020857
 protein coding gene Chr13:102869687-102893815 (-)
C3H/HeJ MGP_C3HHeJ_G0020646
 protein coding gene Chr13:105006148-105029725 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021291
 protein coding gene Chr13:109491067-109516499 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018861
 protein coding gene Chr13:97779559-97803126 (-)
CAST/EiJ MGP_CASTEiJ_G0020164
 protein coding gene Chr13:104445255-104500248 (-)
CBA/J MGP_CBAJ_G0020608
 protein coding gene Chr13:113742460-113768100 (-)
DBA/2J MGP_DBA2J_G0020732
 protein coding gene Chr13:101925849-101949615 (-)
FVB/NJ MGP_FVBNJ_G0020714
 protein coding gene Chr13:100623615-100647027 (-)
LP/J MGP_LPJ_G0020806
 protein coding gene Chr13:106321442-106346729 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020742
 protein coding gene Chr13:113932559-113960897 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021330
 protein coding gene Chr13:104744399-104768545 (-)
PWK/PhJ MGP_PWKPhJ_G0019917
 protein coding gene Chr13:100633812-100685806 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019739
 protein coding gene Chr13:100914557-100967112 (-)
WSB/EiJ MGP_WSBEiJ_G0020223
 protein coding gene Chr13:105213075-105237854 (-)



Homology
more
  • Human Ortholog
    PPWD1, peptidylprolyl isomerase domain and WD repeat containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PPWD1, peptidylprolyl isomerase domain and WD repeat containing 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 23398
    neXtProt AC: NX_Q96BP3
    UniProt: Q96BP3

  • Chr Location
    5q12.3; chr5:65563236-65587549 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 9099
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PPWD1
  • Gene Tree
    Ppwd1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    19
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021713 Ensembl Gene Model | MGI Sequence Detail 23720 C57BL/6J ±  kb
transcript ENSMUST00000022226 Ensembl | MGI Sequence Detail 2342 Not Applicable  
polypeptide ENSMUSP00000022226 Ensembl | MGI Sequence Detail 646 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000013163 peptidylprolyl isomerase domain and WD repeat-containing protein 1
    (term hierarchy)
  • EC
    5.2.1.8
  • InterPro Domains
    IPR029000 Cyclophilin-like domain superfamily
    IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 21
    Genomic 2
    cDNA 19

    Microarray probesets 2
Other
Accession IDs
less
MGI:2444794
References
more
  • Summaries
    All 24
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/03/2019
MGI 6.14 		The Jackson Laboratory