About   Help   FAQ
Agps
Gene Detail
Symbol

Name
ID
Agps
alkylglycerone phosphate synthase
MGI:2443065
Synonyms
9930035G10Rik, ADAPS, bs2
Feature Type
protein coding gene
Genetic Map
Chromosome 2
44.77 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:75832177-75931350 bp, + strand
From VEGA annotation of GRCm38

  99174 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2716  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Agps

Human
homologs
Human Homolog AGPS, alkylglycerone phosphate synthase
NCBI Gene ID 8540
neXtProt AC  NX_O00116
Human Synonyms  ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY
Human Chr (Location)  2q31.2; chr2:177392743-177543836 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human AGPS
Mutations,
alleles, and
phenotypes
All mutations/alleles(118) : Gene trapped(114) Spontaneous(1) Targeted(3)
Genomic Mutations involving Agps (2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a spontaneous allele exhibit male infertility, azoospermia, microphthalmia, and cataracts.
 
Human Diseases Modeled Using Mouse Agps (1)    Alleles Annotated to Human Diseases(1)   
Interactions
Agps interacts with 448 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process lipid biosynthetic process, lipid metabolic process, ...
Component intracellular membrane-bounded organelle, membrane, ...
Function alkylglycerone-phosphate synthase activity, catalytic activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (132)    Tissues (101)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 132
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(17)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000013293 (Evidence)
Ensembl Gene ModelENSMUSG00000042410 (Evidence)
Entrez Gene228061 (Evidence)
DFCITC1579192, TC1752295, TC1646067, TC1624198, TC1644854, TC1597718, TC1589440
DoTSDT.101315541, DT.482012, DT.91334160, DT.110669613, DT.91300027
NIA Mouse Gene IndexU065309, U042317
EC2.5.1.26
Consensus CDS ProjectCCDS16151.2
International Mouse Knockout Project StatusAgps
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013293 VEGA Gene Model | MGI Sequence Detail 99174 C57BL/6J ±  kb
transcript OTTMUST00000032119 VEGA | MGI Sequence Detail 7359 Not Applicable 
polypeptide OTTMUSP00000014280 VEGA | MGI Sequence Detail 671 Not Applicable 

For the selected sequences
All sequences(79) RefSeq(2) UniProt(15)
Polymorphisms
SNPs within 2kb(516 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025650 Alkyldihydroxyacetonephosphate synthase
InterPro IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2
InterPro IPR016166 FAD-binding, type 2
InterPro IPR016167 FAD-binding, type 2, subdomain 1
InterPro IPR004113 FAD-linked oxidase, C-terminal
InterPro IPR016164 FAD-linked oxidase-like, C-terminal
InterPro IPR006094 FAD linked oxidase, N-terminal
Protein Ontology PR:000003842 alkyldihydroxyacetonephosphate synthase, peroxisomal
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(43)
Disease annotation references (1)
Other
accession IDs
MGI:2139316, MGI:3777321

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory