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Agps Gene Detail
Summary
  • Symbol
    Agps
  • Name
    alkylglycerone phosphate synthase
  • Synonyms
    9930035G10Rik, ADAPS, bs2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443065
    NCBI Gene: 228061
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr2:75832177-75931350 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      99174 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 44.77 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    AGPS, alkylglycerone phosphate synthase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AGPS, alkylglycerone phosphate synthase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY, RCDP3
  • Links
    NCBI Gene ID: 8540
    neXtProt AC: NX_O00116
    UniProt: O00116

  • Chr Location
    2q31.2; chr2:177392743-177543836 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 2716
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: AGPS
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with Agps mouse models; 1 with human AGPS associations

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a spontaneous allele exhibit male infertility, azoospermia, microphthalmia, and cataracts.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000013293 VEGA Gene Model | MGI Sequence Detail 99174 C57BL/6J ±  kb
    transcript OTTMUST00000032119 VEGA | MGI Sequence Detail 7359 Not Applicable  
    polypeptide OTTMUSP00000014280 VEGA | MGI Sequence Detail 671 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      515 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      8 Sequences
    • EC
    • InterPro Domains
      IPR025650 Alkyldihydroxyacetonephosphate synthase
      IPR016166 FAD-binding, type 2
      IPR036318 FAD-binding, type 2-like superfamily
      IPR016167 FAD-binding, type 2, subdomain 1
      IPR004113 FAD-linked oxidase, C-terminal
      IPR016164 FAD-linked oxidase-like, C-terminal
      IPR006094 FAD linked oxidase, N-terminal
      IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 18

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2139316, MGI:3777321
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 6
      Phenotypes 16
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:227263 Fabre PJ, et al., Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13964-9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    Funding Information
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    last database update
    07/31/2018
    MGI 6.12
    The Jackson Laboratory