Agps
Gene Detail

Symbol Name ID

Agps alkylglycerone phosphate synthase MGI:2443065

Synonyms

9930035G10Rik, ADAPS, bs2

Feature Type

protein coding gene

Genetic Map

Chromosome 2

44.77 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr2:75832177-75931350 bp, + strand From VEGA annotation of GRCm38   99174 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2716  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Agps

Human homologs

Human Homolog		AGPS, alkylglycerone phosphate synthase
NCBI Gene ID		8540
neXtProt AC		NX_O00116
Human Synonyms		ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY
Human Chr (Location)		2q31.2; chr2:178257471-178408564 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human AGPS

Alleles and phenotypes

All alleles(116) : Targeted(1) Gene trapped(114) Spontaneous(1)
 

Mice homozygous for a spontaneous allele exhibit male infertility, azoospermia, microphthalmia, and cataracts.

 
Human Diseases Modeled Using Mouse Agps (1)    Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	lipid biosynthetic process, lipid metabolic process, ...
Component	intracellular membrane-bounded organelle, mitochondrion, ...
Function	alkylglycerone-phosphate synthase activity, catalytic activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (132)    Tissues (101)    Images (28)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	132

cDNA source data(17)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(17) cDNA(17)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000013293 (Evidence)
Ensembl Gene Model	ENSMUSG00000042410 (Evidence)
Entrez Gene	228061 (Evidence)
DFCI	TC1579192, TC1589440, TC1597718, TC1624198, TC1644854, TC1646067, TC1752295
DoTS	DT.101315541, DT.110669613, DT.482012, DT.91300027, DT.91334160
NIA Mouse Gene Index	U042317, U065309
EC	2.5.1.26
Consensus CDS Project	CCDS16151.2
International Mouse Knockout Project Status	Agps

Sequences

Length	Strain/Species
genomic	OTTMUSG00000013293	VEGA Gene Model | MGI Sequence Detail	99174	C57BL/6J
transcript	OTTMUST00000032119	VEGA | MGI Sequence Detail	7359	Not Applicable
polypeptide	OTTMUSP00000014280	VEGA | MGI Sequence Detail	671	Not Applicable

All sequences(72) RefSeq(2) UniProt(8)

Polymorphisms

SNPs(308 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR025650	Alkyldihydroxyacetonephosphate synthase
InterPro	IPR016166	FAD-binding, type 2
InterPro	IPR016167	FAD-binding, type 2, subdomain 1
InterPro	IPR004113	FAD-linked oxidase, C-terminal
InterPro	IPR016168	FAD-linked oxidase, FAD-binding, subdomain 2
InterPro	IPR016164	FAD-linked oxidase-like, C-terminal
InterPro	IPR006094	FAD linked oxidase, N-terminal
Protein Ontology	PR:000003842	alkyldihydroxyacetonephosphate synthase, peroxisomal

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(41)

Other accession IDs

MGI:2139316, MGI:3777321