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Dnajc27 Gene Detail
Summary
  • Symbol
    Dnajc27
  • Name
    DnaJ heat shock protein family (Hsp40) member C27
  • Synonyms
    C330021A05Rik, Rabj, Rbj
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443036
    NCBI Gene: 217378
Location & Maps
more
  • Sequence Map
    Chr12:4082574-4110612 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      28039 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 1.99 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DNAJC27, DnaJ heat shock protein family (Hsp40) member C27
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DNAJC27, DnaJ heat shock protein family (Hsp40) member C27
    Orthology source: HomoloGene
  • Synonyms
    RabJS, RBJ
  • Links
    NCBI Gene ID: 51277
    neXtProt AC: NX_Q9NZQ0

  • Chr Location
    2p23.3; chr2:24943636-24972094 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    2
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020657 Ensembl Gene Model | MGI Sequence Detail 28039 C57BL/6J ±  kb
transcript ENSMUST00000049584 Ensembl | MGI Sequence Detail 2934 Not Applicable  
polypeptide ENSMUSP00000106803 Ensembl | MGI Sequence Detail 273 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    167 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000031986 DnaJ homolog subfamily C member 27
  • InterPro Domains
    IPR001623 DnaJ domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
less
  • All nucleic 65
    cDNA 65

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144867
References
more
  • Summaries
    All 27
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:210622 Chen T, et al., Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor progression. Cancer Cell. 2014 May 12;25(5):682-96

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory