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Pcid2 Gene Detail
Summary
  • Symbol
    Pcid2
  • Name
    PCI domain containing 2
  • Synonyms
    A730042J05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443003
    NCBI Gene: 234069
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:13077189-13105459 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 5.73 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    439 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443003
protein coding gene Chr8:13075476-13105459 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033371
protein coding gene Chr8:10391910-10421604 (-)
A/J MGP_AJ_G0033351
protein coding gene Chr8:10020855-10050229 (-)
AKR/J MGP_AKRJ_G0033282
protein coding gene Chr8:10289332-10319083 (-)
BALB/cJ MGP_BALBcJ_G0033352
protein coding gene Chr8:10162539-10190702 (-)
C3H/HeJ MGP_C3HHeJ_G0033065
protein coding gene Chr8:10498238-10527782 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033864
protein coding gene Chr8:10760171-10789505 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030833
protein coding gene Chr8:9529039-9559946 (-)
CAST/EiJ MGP_CASTEiJ_G0032387
protein coding gene Chr8:10259719-10287186 (-)
CBA/J MGP_CBAJ_G0033038
protein coding gene Chr8:11208831-11236959 (-)
DBA/2J MGP_DBA2J_G0033191
protein coding gene Chr8:9979837-10007948 (-)
FVB/NJ MGP_FVBNJ_G0033140
protein coding gene Chr8:9985501-10015839 (-)
LP/J MGP_LPJ_G0033285
protein coding gene Chr8:10313787-10343960 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033174
protein coding gene Chr8:11463701-11493208 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033881
protein coding gene Chr8:10357289-10385484 (-)
PWK/PhJ MGP_PWKPhJ_G0032100
protein coding gene Chr8:10025392-10053696 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031942
protein coding gene Chr8:10245113-10277280 (-)
WSB/EiJ MGP_WSBEiJ_G0032503
protein coding gene Chr8:10386542-10416598 (-)



Homology
more
  • Human Ortholog
    PCID2, PCI domain containing 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PCID2, PCI domain containing 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    F10
  • Links
    NCBI Gene ID: 55795
    neXtProt AC: NX_Q5JVF3
    UniProt: Q5JVF3

  • Chr Location
    13q34; chr13:113165002-113209466 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygotes for a targeted null mutation implant, but die prior to embryonic day 7.5. Heterozygotes also exhibit excess embryonic loss.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038542 Ensembl Gene Model | MGI Sequence Detail 28271 C57BL/6J ±  kb
    transcript ENSMUST00000164416 Ensembl | MGI Sequence Detail 2860 Not Applicable  
    polypeptide ENSMUSP00000133204 Ensembl | MGI Sequence Detail 399 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 45
      cDNA 45

      Microarray probesets 7
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:78032 Li B, et al., CUL-4A is critical for early embryonic development. Mol Cell Biol. 2002 Jul;22(14):4997-5005
    • Latest
      J:256297 Ye B, et al., Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2. Nat Commun. 2017 Nov 15;8(1):1518

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory