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Dennd6a Gene Detail
Summary
  • Symbol
    Dennd6a
  • Name
    DENN/MADD domain containing 6A
  • Synonyms
    A630054L15Rik, Fam116a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442980
    NCBI Gene: 211922
Location & Maps
more
  • Sequence Map
    Chr14:26579561-26634322 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      54762 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 16.09 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DENND6A, DENN domain containing 6A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DENND6A, DENN domain containing 6A
    Orthology source: HGNC, HomoloGene
  • Synonyms
    AFI1A, FAM116A
  • Links
    NCBI Gene ID: 201627
    neXtProt AC: NX_Q8IWF6

  • Chr Location
    3p14.3; chr3:57625454-57693089 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    45
  • Gene trapped
    43
  • Targeted
    2
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000056602 VEGA Gene Model | MGI Sequence Detail 54762 C57BL/6J ±  kb
transcript OTTMUST00000139755 VEGA | MGI Sequence Detail 6638 Not Applicable  
polypeptide OTTMUSP00000073304 VEGA | MGI Sequence Detail 605 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    211 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 43
    cDNA 43

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory