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Dennd6a Gene Detail
Summary
  • Symbol
    Dennd6a
  • Name
    DENN/MADD domain containing 6A
  • Synonyms
    A630054L15Rik, Fam116a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442980
    NCBI Gene: 211922
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:26573858-26634322 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 16.09 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    211 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442980
protein coding gene Chr14:26573856-26634322 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021082
protein coding gene Chr14:19554920-19614665 (+)
A/J MGP_AJ_G0021031
protein coding gene Chr14:18782845-18838964 (+)
AKR/J MGP_AKRJ_G0021008
protein coding gene Chr14:19816469-19872776 (+)
BALB/cJ MGP_BALBcJ_G0021034
protein coding gene Chr14:18897911-18953975 (+)
C3H/HeJ MGP_C3HHeJ_G0020818
protein coding gene Chr14:19675694-19734008 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021467
protein coding gene Chr14:20377498-20436195 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019030
protein coding gene Chr14:18941868-18999568 (+)
CAST/EiJ MGP_CASTEiJ_G0020342
protein coding gene Chr14:19281348-19339605 (+)
CBA/J MGP_CBAJ_G0020784
protein coding gene Chr14:21191939-21246387 (+)
DBA/2J MGP_DBA2J_G0020907
protein coding gene Chr14:18869499-18924477 (+)
FVB/NJ MGP_FVBNJ_G0020890
protein coding gene Chr14:18833615-18888329 (+)
LP/J MGP_LPJ_G0020975
protein coding gene Chr14:19826876-19881856 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020916
protein coding gene Chr14:20522960-20582595 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021500
protein coding gene Chr14:19578741-19634014 (+)
PWK/PhJ MGP_PWKPhJ_G0020091
protein coding gene Chr14:18239660-18297985 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019914
protein coding gene Chr14:19053767-19112097 (+)
WSB/EiJ MGP_WSBEiJ_G0020398
protein coding gene Chr14:19619023-19677684 (+)



Homology
more
  • Human Ortholog
    DENND6A, DENN domain containing 6A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DENND6A, DENN domain containing 6A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AFI1A, FAM116A
  • Links
    NCBI Gene ID: 201627
    neXtProt AC: NX_Q8IWF6
    UniProt: Q8IWF6

  • Chr Location
    3p14.3; chr3:57625454-57693118 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 211922 NCBI Gene Model | MGI Sequence Detail 60465 C57BL/6J ±  kb
transcript NM_001285467 RefSeq | MGI Sequence Detail 6727 C57BL/6  
polypeptide Q8BH65 UniProt | EBI | MGI Sequence Detail 605 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 45
    cDNA 45

    Microarray probesets 4
References
more
  • Summaries
    All 27
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory