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Ogfod1 Gene Detail
Summary
  • Symbol
    Ogfod1
  • Name
    2-oxoglutarate and iron-dependent oxygenase domain containing 1
  • Synonyms
    4930415J21Rik, mKIAA1612
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442978
    NCBI Gene: 270086
  • Gene Overview
    MyGene.info: OGFOD1
Location & Maps
more
  • Sequence Map
    Chr8:94037198-94067921 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30724 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 46.08 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    OGFOD1, 2-oxoglutarate and iron dependent oxygenase domain containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    OGFOD1, 2-oxoglutarate and iron dependent oxygenase domain containing 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    TPA1
  • Links
    NCBI Gene ID: 55239
    neXtProt AC: NX_Q8N543

  • Chr Location
    16q12.2; chr16:56451417-56477495 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Mice homozygous for a null allele are viable and fertile.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023230 VEGA Gene Model | MGI Sequence Detail 30724 C57BL/6J ±  kb
transcript OTTMUST00000056238 VEGA | MGI Sequence Detail 5310 Not Applicable  
polypeptide OTTMUSP00000027002 VEGA | MGI Sequence Detail 545 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    183 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000031159 prolyl 3-hydroxylase OGFOD1
  • EC
  • InterPro Domains
    IPR005123 Oxoglutarate/iron-dependent dioxygenase
    IPR019601 Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain
    IPR006620 Prolyl 4-hydroxylase, alpha subunit
Molecular
Reagents
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  • All nucleic 58
    cDNA 58

    Microarray probesets 4
Other
Accession IDs
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MGI:2142755, MGI:3034504, MGI:3035372
References
more
  • Summaries
    All 29
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:207410 Singleton RS, et al., OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4031-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory