Minar2 Gene Detail

Summary

• Symbol
  Minar2
• Name
  membrane integral NOTCH2 associated receptor 2
• Synonyms
  A730017C20Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2442934
  NCBI Gene: 225583
• Alliance
  gene page
• Transcription Start Sites
  4 TSS

Location &
Maps

• Sequence Map
  Chr18:59062248-59076962 bp, + strand
• From Ensembl annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 18, 33.90 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  185 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2442934	protein coding gene	Chr18:59062189-59076962 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0024456	protein coding gene	Chr18:58646541-58662122 (+)
A/J	MGP_AJ_G0024422	protein coding gene	Chr18:56253592-56268291 (+)
AKR/J	MGP_AKRJ_G0024392	protein coding gene	Chr18:57805546-57821709 (+)
BALB/cJ	MGP_BALBcJ_G0024422	protein coding gene	Chr18:56408463-56423998 (+)
C3H/HeJ	MGP_C3HHeJ_G0024189	protein coding gene	Chr18:58021281-58035976 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0024868	protein coding gene	Chr18:60452140-60470935 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022300	protein coding gene	Chr18:55796934-55812237 (+)
CAST/EiJ	MGP_CASTEiJ_G0023663	protein coding gene	Chr18:58038972-58053700 (+)
CBA/J	MGP_CBAJ_G0024159	protein coding gene	Chr18:62412578-62432272 (+)
DBA/2J	MGP_DBA2J_G0024289	protein coding gene	Chr18:55960914-55978277 (+)
FVB/NJ	MGP_FVBNJ_G0024256	protein coding gene	Chr18:55327366-55342278 (+)
LP/J	MGP_LPJ_G0024374	protein coding gene	Chr18:58556347-58571780 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024286	protein coding gene	Chr18:63918416-63936277 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0024915	protein coding gene	Chr18:57934943-57950688 (+)
PWK/PhJ	MGP_PWKPhJ_G0023407	protein coding gene	Chr18:55979595-55994469 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023213	protein coding gene	Chr18:58004692-58019772 (+)
WSB/EiJ	MGP_WSBEiJ_G0023726	protein coding gene	Chr18:57833578-57849347 (+)

Homology

• Human Ortholog
  MINAR2, membrane integral NOTCH2 associated receptor 2

• Vertebrate Orthologs
  10

• Human Ortholog
  MINAR2, membrane integral NOTCH2 associated receptor 2
  Orthology source: HomoloGene, HGNC
• Synonyms
  KIAA1024L
• Links
  HGNC:33914

  NCBI Gene ID: 100127206

  neXtProt AC: NX_P59773

  UniProt: P59773

  
  
• Chr Location
  5q23.3; chr5:129748191-129765063 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 18350
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: MINAR2
• Gene Tree
  Minar2
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  10 phenotypes from 1 allele in 1 genetic background
  7 phenotype references
  

• All Mutations and Alleles
  5
• Targeted
  5
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  14 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  1

• External Resources
  FuncBase

Expression

• cDNA Data
  44

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Minar2 interacts with 206 markers (Mir1a-1, Mir1a-2, Mir9-1, ...) View All

Sequences &
Gene Models

• All Sequences
  58
• RefSeq
  10
• UniProt
  3
• CCDS
  CCDS29267.2
• UniGene
  209711

• Ensembl
  ENSMUSG00000050875 (Evidence)
• NCBI Gene
  225583

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000050875	Ensembl Gene Model | MGI Sequence Detail	14715	C57BL/6J
transcript	ENSMUST00000165666	Ensembl | MGI Sequence Detail	1911	Not Applicable
polypeptide	ENSMUSP00000125952	Ensembl | MGI Sequence Detail	193	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• InterPro Domains
  IPR039706 Major intrinsically disordered Notch2-binding receptor 1-like
  IPR009626 Major intrinsically disordered Notch2-binding receptor 1-like, C-terminal

Molecular
Reagents

• All nucleic 44

  cDNA 44

  
  

  Microarray probesets 5

References

• Summaries
  All 25

  Gene Ontology 1

  Phenotypes 7
• Earliest
  J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
• Latest
  J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

TSS for Minar2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr5340	Chr18:59062312-59062338 (+)	77 bp
Tssr151231	Chr18:59062344-59062376 (+)	112 bp
Tssr151232	Chr18:59062379-59062389 (+)	136 bp
Tssr151233	Chr18:59062488-59062538 (+)	265 bp