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Minar2 Gene Detail
Summary
  • Symbol
    Minar2
  • Name
    membrane integral NOTCH2 associated receptor 2
  • Synonyms
    A730017C20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442934
    NCBI Gene: 225583
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:59195320-59210034 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 33.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    160 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442934
 protein coding gene Chr18:59195264-59210034 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024456
 protein coding gene Chr18:58646541-58662122 (+)
A/J MGP_AJ_G0024422
 protein coding gene Chr18:56253592-56268291 (+)
AKR/J MGP_AKRJ_G0024392
 protein coding gene Chr18:57805546-57821709 (+)
BALB/cJ MGP_BALBcJ_G0024422
 protein coding gene Chr18:56408463-56423998 (+)
C3H/HeJ MGP_C3HHeJ_G0024189
 protein coding gene Chr18:58021281-58035976 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024868
 protein coding gene Chr18:60452140-60470935 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022300
 protein coding gene Chr18:55796934-55812237 (+)
CAST/EiJ MGP_CASTEiJ_G0023663
 protein coding gene Chr18:58038972-58053700 (+)
CBA/J MGP_CBAJ_G0024159
 protein coding gene Chr18:62412578-62432272 (+)
DBA/2J MGP_DBA2J_G0024289
 protein coding gene Chr18:55960914-55978277 (+)
FVB/NJ MGP_FVBNJ_G0024256
 protein coding gene Chr18:55327366-55342278 (+)
LP/J MGP_LPJ_G0024374
 protein coding gene Chr18:58556347-58571780 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024286
 protein coding gene Chr18:63918416-63936277 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024915
 protein coding gene Chr18:57934943-57950688 (+)
PWK/PhJ MGP_PWKPhJ_G0023407
 protein coding gene Chr18:55979595-55994469 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023213
 protein coding gene Chr18:58004692-58019772 (+)
WSB/EiJ MGP_WSBEiJ_G0023726
 protein coding gene Chr18:57833578-57849347 (+)



Homology
more
  • Human Ortholog
    MINAR2, membrane integral NOTCH2 associated receptor 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MINAR2, membrane integral NOTCH2 associated receptor 2
  • Synonyms
    KIAA1024L
  • Links
    NCBI Gene ID: 100127206
    neXtProt AC: NX_P59773
    UniProt: P59773

  • Chr Location
    5q23.3; chr5:129748191-129765063 (+)  GRCh38.p7
Human Diseases
more
  • Diseases
    1 with Minar2 mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    672
  • cDNA Data
    44
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000050875 Ensembl Gene Model | MGI Sequence Detail 14715 C57BL/6J ±  kb
    transcript ENSMUST00000165666 Ensembl | MGI Sequence Detail 1911 Not Applicable  
    polypeptide ENSMUSP00000125952 Ensembl | MGI Sequence Detail 193 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000059768 major intrinsically disordered NOTCH2-binding receptor 1-like
      (term hierarchy)
    • InterPro Domains
      IPR039706 Major intrinsically disordered Notch2-binding receptor 1-like
      IPR009626 Major intrinsically disordered Notch2-binding receptor 1-like, C-terminal
    Molecular
    Reagents
    less
    • All nucleic 44
      cDNA 44

      Microarray probesets 5
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 1
      Phenotypes 8
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:326355 Bademci G, et al., Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice. Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2204084119
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.     		last database update
    08/09/2022
    MGI 6.21     		The Jackson Laboratory