About   Help   FAQ
Tmprss11b
Gene Detail
 Symbol
Name
ID
Tmprss11b
transmembrane protease, serine 11B
MGI:2442893
Synonyms 9930019B18Rik, Tmprss11bnl
Feature Type protein coding gene
Genetic Map
Chromosome 5
43.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:86657631-86676362 bp, - strand
From VEGA annotation of GRCm38

  18732 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:64599  Vertebrate Homology Class
1 mouse; 1 rat; 1 cattle; 1 dog

Protein SuperFamily: transmembrane serine protease, TMPRSS11A type
Gene Tree: Tmprss11b

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tmprss11b interacts with 303 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process proteolysis
Component extracellular region, integral component of membrane, ...
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000035106 (Evidence)
Ensembl Gene ModelENSMUSG00000035861 (Evidence)
Entrez Gene319875 (Evidence)
UniGene253994
DFCITC1590357
DoTSDT.91322243
NIA Mouse Gene IndexU026352
EC3.4.21.-
Consensus CDS ProjectCCDS39126.1
International Mouse Knockout Project StatusTmprss11b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035106 VEGA Gene Model | MGI Sequence Detail 18732 C57BL/6J ±  kb
transcript OTTMUST00000089306 VEGA | MGI Sequence Detail 4171 Not Applicable 
polypeptide OTTMUSP00000048795 VEGA | MGI Sequence Detail 416 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(130 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR017329 Peptidase S1A, HAT/DESC1
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR000082 SEA domain
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000016449 transmembrane protease serine 11B
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory