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Tmprss11b Gene Detail
Summary
  • Symbol
    Tmprss11b
  • Name
    transmembrane protease, serine 11B
  • Synonyms
    9930019B18Rik, Tmprss11bnl
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442893
    NCBI Gene: 319875
Location & Maps
more
  • Sequence Map
    Chr5:86657631-86676362 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      18732 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 43.56 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TMPRSS11B, transmembrane protease, serine 11B
  • Vertebrate Orthologs
    4
  • Human Ortholog
    TMPRSS11B, transmembrane protease, serine 11B
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 132724
    neXtProt AC: NX_Q86T26

  • Chr Location
    4q13.2; chr4:68226653-68245694 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    5
  • Genomic Mutations
    4 involving Tmprss11b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035106 VEGA Gene Model | MGI Sequence Detail 18732 C57BL/6J ±  kb
transcript OTTMUST00000089306 VEGA | MGI Sequence Detail 4171 Not Applicable  
polypeptide OTTMUSP00000048795 VEGA | MGI Sequence Detail 416 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    130 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory