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Eda2r Gene Detail
Summary
  • Symbol
    Eda2r
  • Name
    ectodysplasin A2 receptor
  • Synonyms
    9430060M22Rik, Xedar
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442860
    NCBI Gene: 245527
  • Gene Overview
    MyGene.info: EDA2R
Location & Maps
more
  • Sequence Map
    ChrX:97333840-97377216 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      43377 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 42.74 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    EDA2R, ectodysplasin A2 receptor
  • Vertebrate Orthologs
    8
  • Human Ortholog
    EDA2R, ectodysplasin A2 receptor
    Orthology source: HGNC, HomoloGene
  • Synonyms
    EDAA2R, EDA-A2R, TNFRSF27, XEDAR
  • Links
    NCBI Gene ID: 60401
    neXtProt AC: NX_Q9HAV5

  • Chr Location
    Xq12; chrX:66594384-66639298 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
  • All Mutations and Alleles
    9
  • Gene trapped
    7
  • Targeted
    2
Hemizygous null males are fertile and healthy with no histological abnormalities in any of the major organs.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018046 VEGA Gene Model | MGI Sequence Detail 43377 C57BL/6J ±  kb
transcript OTTMUST00000043555 VEGA | MGI Sequence Detail 4752 Not Applicable  
polypeptide OTTMUSP00000019574 VEGA | MGI Sequence Detail 297 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    120 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000006887 tumor necrosis factor receptor superfamily member 27
  • InterPro Domains
    IPR001368 TNFR/NGFR cysteine-rich region
    IPR022319 Tumour necrosis factor receptor 27
Molecular
Reagents
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  • All nucleic 19
    cDNA 17
    Primer pair 1
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:221155 Quintens R, et al., Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development. Biol Open. 2015;4(3):331-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory