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Tshz3
Gene Detail
Symbol

Name
ID
Tshz3
teashirt zinc finger family member 3
MGI:2442819
Synonyms
A630038G13Rik, teashirt3, Tsh3, Zfp537
Feature Type
protein coding gene
Genetic Map
Chromosome 7
22.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:36698118-36773553 bp, + strand
From VEGA annotation of GRCm38

  75436 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10835  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Tshz3

Human
homologs
Human Homolog TSHZ3, teashirt zinc finger homeobox 3
NCBI Gene ID 57616
neXtProt AC  NX_Q63HK5
Human Synonyms  TSH3, ZNF537
Human Chr (Location)  19q12; chr19:31274945-31349284 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit neoatal lethality likely due to respiratory distress and hydroureter and hydronephrosis associated with impaired development of ureteric smooth muscle.
 
Interactions
Tshz3 interacts with 363 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process in utero embryonic development, kidney morphogenesis, ...
Component cell projection, growth cone, ...
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (17 records)
Data Summary: Results (211)    Tissues (181)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 209
RT-PCR 2
cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(21) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000040171 (Evidence)
Ensembl Gene ModelENSMUSG00000021217 (Evidence)
Entrez Gene243931 (Evidence)
UniGene44141
DFCITC1582137
DoTSDT.40138279
NIA Mouse Gene IndexU007979
Consensus CDS ProjectCCDS39913.1
International Mouse Knockout Project StatusTshz3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000040171 VEGA Gene Model | MGI Sequence Detail 75436 C57BL/6J ±  kb
transcript OTTMUST00000104432 VEGA | MGI Sequence Detail 5098 Not Applicable 
polypeptide OTTMUSP00000058445 VEGA | MGI Sequence Detail 1081 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(14) UniProt(9)
Polymorphisms
SNPs within 2kb(841 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR027008 Teashirt family
InterPro IPR026810 Teashirt homologue 3
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
Protein Ontology PR:000016727 teashirt homolog 3
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:210128 Weiss RM, et al., Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26
All references(48)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory