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Trim65 Gene Detail
Summary
  • Symbol
    Trim65
  • Name
    tripartite motif-containing 65
  • Synonyms
    4732463G12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442815
    NCBI Gene: 338364
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:116124708-116131260 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 80.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442815
protein coding gene Chr11:116121846-116131260 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019415
protein coding gene Chr11:120211008-120220680 (-)
A/J MGP_AJ_G0019384
protein coding gene Chr11:114958940-114968462 (-)
AKR/J MGP_AKRJ_G0019354
protein coding gene Chr11:118385775-118395099 (-)
BALB/cJ MGP_BALBcJ_G0019358
protein coding gene Chr11:115369540-115378864 (-)
C3H/HeJ MGP_C3HHeJ_G0019164
protein coding gene Chr11:118740007-118749279 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019808
protein coding gene Chr11:123893788-123907681 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017431
protein coding gene Chr11:111973030-111981933 (-)
CAST/EiJ MGP_CASTEiJ_G0018719
protein coding gene Chr11:120094898-120104181 (-)
CBA/J MGP_CBAJ_G0019136
protein coding gene Chr11:128784005-128793282 (-)
DBA/2J MGP_DBA2J_G0019247
protein coding gene Chr11:114375099-114384562 (-)
FVB/NJ MGP_FVBNJ_G0019239
protein coding gene Chr11:113890104-113899573 (-)
LP/J MGP_LPJ_G0019317
protein coding gene Chr11:120592311-120601615 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019272
protein coding gene Chr11:127874331-127883838 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019846
protein coding gene Chr11:119045619-119055642 (-)
PWK/PhJ MGP_PWKPhJ_G0018483
protein coding gene Chr11:115711869-115721470 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018276
protein coding gene Chr11:118799194-118808369 (-)
WSB/EiJ MGP_WSBEiJ_G0018771
protein coding gene Chr11:119008624-119018558 (-)



Homology
more
  • Human Ortholog
    TRIM65, tripartite motif containing 65
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TRIM65, tripartite motif containing 65
    Orthology source: HomoloGene, HGNC
  • Synonyms
    4732463G12Rik
  • Links
    NCBI Gene ID: 201292
    neXtProt AC: NX_Q6PJ69
    UniProt: Q6PJ69

  • Chr Location
    17q25.1; chr17:75880379-75897008 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 338364 NCBI Gene Model | MGI Sequence Detail 6553 C57BL/6J ±  kb
transcript NM_178802 RefSeq | MGI Sequence Detail 3050 C57BL/6  
polypeptide Q8BFW4 UniProt | EBI | MGI Sequence Detail 522 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:240099 Lang X, et al., TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity. J Exp Med. 2017 Feb;214(2):459-473

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory