About   Help   FAQ
Cadm2 Gene Detail
Summary
  • Symbol
    Cadm2
  • Name
    cell adhesion molecule 2
  • Synonyms
    2900078E11Rik, A830029E02Rik, Igsf4d, Necl3, SynCAM2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442722
    NCBI Gene: 239857
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:66655421-67620908 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 37.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4082 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442722
protein coding gene Chr16:66655416-67621202 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022947
protein coding gene Chr16:66232930-67281478 (-)
A/J MGP_AJ_G0022915
protein coding gene Chr16:63372620-64351974 (-)
AKR/J MGP_AKRJ_G0022885
protein coding gene Chr16:65376530-66359344 (-)
BALB/cJ MGP_BALBcJ_G0022917
protein coding gene Chr16:63595803-64591288 (-)
C3H/HeJ MGP_C3HHeJ_G0022679
protein coding gene Chr16:65667652-66699897 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023365
protein coding gene Chr16:68197858-69277064 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020868
protein coding gene Chr16:62322810-63255346 (-)
CAST/EiJ MGP_CASTEiJ_G0022202
protein coding gene Chr16:65884893-66965508 (-)
CBA/J MGP_CBAJ_G0022650
protein coding gene Chr16:71113030-72208772 (-)
DBA/2J MGP_DBA2J_G0022782
protein coding gene Chr16:63160072-64133885 (-)
FVB/NJ MGP_FVBNJ_G0022756
protein coding gene Chr16:62729177-63697416 (-)
LP/J MGP_LPJ_G0022851
protein coding gene Chr16:66045082-67110008 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022775
protein coding gene Chr16:72455901-73833488 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023381
protein coding gene Chr16:65465845-66497867 (-)
PWK/PhJ MGP_PWKPhJ_G0021945
protein coding gene Chr16:63313605-64309474 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021774
protein coding gene Chr16:65138996-66163712 (-)
WSB/EiJ MGP_WSBEiJ_G0022249
protein coding gene Chr16:65518809-66584840 (-)



Homology
more
  • Human Ortholog
    CADM2, cell adhesion molecule 2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    CADM2, cell adhesion molecule 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IGSF4D, Necl-3, NECL3, synCAM2, SynCAM 2
  • Links
    NCBI Gene ID: 253559
    neXtProt AC: NX_Q8N3J6
    UniProt: Q8N3J6

  • Chr Location
    3p12.1; chr3:84958982-86074429 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 17705
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CADM2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Mice with ubiquitous conditional deletion of the gene do not display any neurological abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064115 Ensembl Gene Model | MGI Sequence Detail 965488 C57BL/6J ±  kb
transcript ENSMUST00000120594 Ensembl | MGI Sequence Detail 3248 Not Applicable  
polypeptide ENSMUSP00000113500 Ensembl | MGI Sequence Detail 435 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 7
Other
Accession IDs
less
MGI:1920236
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:260828 Yan X, et al., Cadm2 regulates body weight and energy homeostasis in mice. Mol Metab. 2018 Feb;8:180-188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory