About   Help   FAQ
Klhdc8a Gene Detail
Summary
  • Symbol
    Klhdc8a
  • Name
    kelch domain containing 8A
  • Synonyms
    A630065K24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442630
    NCBI Gene: 213417
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:132298626-132307357 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 57.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442630
protein coding gene Chr1:132298490-132307357 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016469
protein coding gene Chr1:135774277-135782996 (+)
A/J MGP_AJ_G0016452
protein coding gene Chr1:130741455-130750185 (+)
AKR/J MGP_AKRJ_G0016417
protein coding gene Chr1:134589242-134597961 (+)
BALB/cJ MGP_BALBcJ_G0016412
protein coding gene Chr1:131075361-131084083 (+)
C3H/HeJ MGP_C3HHeJ_G0016238
protein coding gene Chr1:134737605-134746335 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016873
protein coding gene Chr1:140815474-140824204 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014584
protein coding gene Chr1:123885993-123895123 (+)
CAST/EiJ MGP_CASTEiJ_G0015818
protein coding gene Chr1:133731787-133740554 (+)
CBA/J MGP_CBAJ_G0016210
protein coding gene Chr1:145623424-145632147 (+)
DBA/2J MGP_DBA2J_G0016317
protein coding gene Chr1:129705594-129714313 (+)
FVB/NJ MGP_FVBNJ_G0016316
protein coding gene Chr1:128336884-128345611 (+)
LP/J MGP_LPJ_G0016388
protein coding gene Chr1:137083514-137092236 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016341
protein coding gene Chr1:151423791-151432519 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016909
protein coding gene Chr1:134343275-134352032 (+)
PWK/PhJ MGP_PWKPhJ_G0015604
protein coding gene Chr1:128696700-128705488 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015391
protein coding gene Chr1:133301625-133311613 (+)
WSB/EiJ MGP_WSBEiJ_G0015880
protein coding gene Chr1:134339973-134348697 (+)



Homology
more
  • Human Ortholog
    KLHDC8A, kelch domain containing 8A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KLHDC8A, kelch domain containing 8A
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55220
    neXtProt AC: NX_Q8IYD2
    UniProt: Q8IYD2

  • Chr Location
    1q32.1; chr1:205336065-205357090 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    3 involving Klhdc8a
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042115 Ensembl Gene Model | MGI Sequence Detail 8732 C57BL/6J ±  kb
transcript ENSMUST00000046071 Ensembl | MGI Sequence Detail 4269 Not Applicable  
polypeptide ENSMUSP00000038297 Ensembl | MGI Sequence Detail 350 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Developmental Gene Expression 2
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/21/2020
MGI 6.14
The Jackson Laboratory