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Frmd6 Gene Detail
Summary
  • Symbol
    Frmd6
  • Name
    FERM domain containing 6
  • Synonyms
    2610019M19Rik, 4930488L10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442579
    NCBI Gene: 319710
  • Gene Overview
    MyGene.info: FRMD6
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:70825514-70902234 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 29.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    682 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442579
protein coding gene Chr12:70825335-70902234 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019811
protein coding gene Chr12:70594925-70673862 (+)
A/J MGP_AJ_G0019769
protein coding gene Chr12:67959438-68036506 (+)
AKR/J MGP_AKRJ_G0019745
protein coding gene Chr12:69989726-70070610 (+)
BALB/cJ MGP_BALBcJ_G0019749
protein coding gene Chr12:68416413-68493515 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0020201
protein coding gene Chr12:72851324-72932906 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017821
protein coding gene Chr12:65475167-65549628 (+)
CAST/EiJ MGP_CASTEiJ_G0019106
protein coding gene Chr12:65221496-65299915 (+)
CBA/J MGP_CBAJ_G0019524
protein coding gene Chr12:75540889-75623665 (+)
DBA/2J MGP_DBA2J_G0019640
protein coding gene Chr12:67864938-67942159 (+)
FVB/NJ MGP_FVBNJ_G0019627
protein coding gene Chr12:66763708-66842618 (+)
LP/J MGP_LPJ_G0019712
protein coding gene Chr12:70585638-70663583 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020236
protein coding gene Chr12:69488825-69567831 (+)
PWK/PhJ MGP_PWKPhJ_G0018871
protein coding gene Chr12:62148036-62226922 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018666
protein coding gene Chr12:63861854-63938551 (+)
WSB/EiJ MGP_WSBEiJ_G0019157
protein coding gene Chr12:70097424-70176316 (+)



Homology
more
  • Human Ortholog
    FRMD6, FERM domain containing 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FRMD6, FERM domain containing 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    c14_5320, C14orf31, EX1, Willin
  • Links
    NCBI Gene ID: 122786
    neXtProt AC: NX_Q96NE9
    UniProt: Q96NE9

  • Chr Location
    14q22.1; chr14:51489100-51730727 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 12449
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FRMD6
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048285 Ensembl Gene Model | MGI Sequence Detail 76721 C57BL/6J ±  kb
transcript ENSMUST00000057859 Ensembl | MGI Sequence Detail 4662 Not Applicable  
polypeptide ENSMUSP00000052202 Ensembl | MGI Sequence Detail 622 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1919400, MGI:2145018
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:213985 Ishiuchi T, et al., Nectins localize Willin to cell-cell junctions. Genes Cells. 2012 May;17(5):387-97

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory