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Stk38
Gene Detail
Symbol

Name
ID
Stk38
serine/threonine kinase 38
MGI:2442572
Synonyms
5830476G13Rik, 9530097A09Rik, Ndr1
Feature Type
protein coding gene
Genetic Map
Chromosome 17
15.03 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:28970885-29007945 bp, - strand
From VEGA annotation of GRCm38

  37061 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56033  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: STK38
Protein SuperFamily: serine/threonine-protein kinase, Ndr (nuclear Dbf2-related) type
Gene Tree: Stk38

Human
homologs
STK38, serine/threonine kinase 38
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 11329
neXtProt AC: NX_Q15208

Human Synonyms: NDR, NDR1

Human Chr (Location): 6p21; chr6:36493889-36547479 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(94) : Gene trapped(92) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Stk38 interacts with 285 markers (Mir10a, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cellular protein modification process, intracellular signal transduction, ...
Component cytoplasm, MLL5-L complex, ...
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (125)    Tissues (99)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 125
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase stk38 ; ZFIN stk38a    NEW 
Molecular
reagents
All nucleic(16) cDNA(15) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000031637 (Evidence)
Ensembl Gene Model ENSMUSG00000024006 (Evidence)
Entrez Gene 106504 (Evidence)
DFCI TC1708858, TC1645404, TC1573064, TC1594260
DoTS DT.60105152, DT.110574609, DT.493214, DT.94372489, DT.101378017, DT.101258622
NIA Mouse Gene Index U037619
EC 2.7.11.1
Consensus CDS Project CCDS28589.1
International Mouse Phenotyping Consortium Status Stk38
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031637 VEGA Gene Model | MGI Sequence Detail 37061 C57BL/6J ±  kb
transcript OTTMUST00000078369 VEGA | MGI Sequence Detail 3288 Not Applicable 
polypeptide OTTMUSP00000041672 VEGA | MGI Sequence Detail 465 Not Applicable 

For the selected sequences
All sequences(92) RefSeq(18) UniProt(4)
Polymorphisms
SNPs within 2kb(127 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000961 AGC-kinase, C-terminal
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR017892 Protein kinase, C-terminal
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000015754 serine/threonine-protein kinase 38
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:175077 Zhou Y, et al., MICAL-1 Is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis. Mol Cell Biol. 2011 Sep;31(17):3603-15
All references(38)
Other
accession IDs
MGI:1924472, MGI:2146777

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory