Mroh1 Gene Detail

Summary

• Symbol
  Mroh1
• Name
  maestro heat-like repeat family member 1
• Synonyms
  D330001F17Rik, Heatr7a, mKIAA1833

• Feature Type
  protein coding gene
• IDs
  MGI:2442558
  NCBI Gene: 223658

Location & Maps

• Sequence Map
  Chr15:76380261-76453038 bp, + strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    72778 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 15, 35.80 cM
• Mapping Data
  1 experiment

Homology

• Human Ortholog
  MROH1, maestro heat like repeat family member 1

• Vertebrate Orthologs
  8

• Human Ortholog
  MROH1, maestro heat like repeat family member 1
  Orthology source: HomoloGene, HGNC
• Synonyms
  HEATR7A
• Links
  HGNC:26958

  NCBI Gene ID: 727957

  neXtProt AC: NX_Q8NDA8

  UniProt: Q8NDA8

  
  
• Chr Location
  8q24.3; chr8:144148016-144261940 (+)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 44882
  1 human;1 mouse;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: MROH1
• Gene Tree
  Mroh1
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  25 phenotype references
  

• All Mutations and Alleles
  7
• Chemically induced (other)
  3
• Gene trapped
  1
• Radiation induced
  2
• Targeted
  1
• Genomic Mutations
  5 involving Mroh1
• Incidental Mutations
  APF
• Find Mice (IMSR)
  26 strains or lines available

Gene Ontology
(GO)
Classifications

• External Resources
  FuncBase

Expression

• cDNA Data
  102

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Mroh1 interacts with 302 markers (Mir1a-1, Mir1a-2, Mir7-1, ...) View All

Sequences &
Gene Models

• All Sequences
  132
• RefSeq
  30
• UniProt
  9
• CCDS
  CCDS49651.1, CCDS49652.1
• UniGene
  123240

• VEGA
  OTTMUSG00000032529 (Evidence)
• Ensembl
  ENSMUSG00000022558 (Evidence)
• NCBI Gene
  223658

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000032529	VEGA Gene Model | MGI Sequence Detail	72778	C57BL/6J
transcript	OTTMUST00000081367	VEGA | MGI Sequence Detail	5268	Not Applicable
polypeptide	OTTMUSP00000043521	VEGA | MGI Sequence Detail	1640	Not Applicable

Polymorphisms

• SNPs within 2kb
  416 from dbSNP Build 142

Protein
Information

• UniProt
  9 Sequences
• InterPro Domains
  IPR011989 Armadillo-like helical
  IPR016024 Armadillo-type fold
  IPR021133 HEAT, type 2

Molecular
Reagents

• All nucleic 102

  cDNA 102

  
  

  Microarray probesets 6

References

• Summaries
  All 43

  Diseases 1

  Phenotypes 25
• Earliest
  J:13437 Bangham JW, Hairy ears, Eh. Mouse News Lett. 1965;33:68
• Latest
  J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9