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Mroh1 Gene Detail
Summary
  • Symbol
    Mroh1
  • Name
    maestro heat-like repeat family member 1
  • Synonyms
    D330001F17Rik, Heatr7a, mKIAA1833
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442558
    NCBI Gene: 223658
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76264638-76337239 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 35.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4254 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442558
 protein coding gene Chr15:76264461-76337239 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021991
 protein coding gene Chr15:76452886-76527776 (+)
A/J MGP_AJ_G0021949
 protein coding gene Chr15:73669377-73742057 (+)
AKR/J MGP_AKRJ_G0021932
 protein coding gene Chr15:75669735-75742024 (+)
BALB/cJ MGP_BALBcJ_G0021958
 protein coding gene Chr15:73696889-73769750 (+)
C3H/HeJ MGP_C3HHeJ_G0021730
 protein coding gene Chr15:75715098-75789498 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022398
 protein coding gene Chr15:79320846-79394497 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019927
 protein coding gene Chr15:70328676-70403630 (+)
CAST/EiJ MGP_CASTEiJ_G0021249
 protein coding gene Chr15:76511717-76591705 (+)
CBA/J MGP_CBAJ_G0021697
 protein coding gene Chr15:81819325-81897872 (+)
DBA/2J MGP_DBA2J_G0021822
 protein coding gene Chr15:73203724-73279119 (+)
FVB/NJ MGP_FVBNJ_G0021802
 protein coding gene Chr15:72258855-72332648 (+)
LP/J MGP_LPJ_G0021893
 protein coding gene Chr15:76546530-76626135 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021827
 protein coding gene Chr15:87151472-87233111 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022418
 protein coding gene Chr15:75911098-75993542 (+)
PWK/PhJ MGP_PWKPhJ_G0020990
 protein coding gene Chr15:73363335-73441194 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020830
 protein coding gene Chr15:75631416-75708853 (+)
WSB/EiJ MGP_WSBEiJ_G0021301
 protein coding gene Chr15:76016250-76097479 (+)



Homology
more
  • Human Ortholog
    MROH1, maestro heat like repeat family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MROH1, maestro heat like repeat family member 1
  • Synonyms
    HEATR7A
  • Links
    NCBI Gene ID: 727957
    UniProt: Q8NDA8

  • Chr Location
    8q24.3; chr8:144148016-144261927 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    1
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    5 involving Mroh1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    63 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    103
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 223658 NCBI Gene Model | MGI Sequence Detail 72602 C57BL/6J ±  kb
transcript NM_175457 RefSeq | MGI Sequence Detail 5269 C57BL/6  
polypeptide E0CZ22 UniProt | EBI | MGI Sequence Detail 1640 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 103
    cDNA 103

    Microarray probesets 6
References
more
  • Summaries
    All 47
    Diseases 1
    Gene Ontology 2
    Phenotypes 27
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory