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Slc6a17 Gene Detail
Summary
  • Symbol
    Slc6a17
  • Name
    solute carrier family 6 (neurotransmitter transporter), member 17
  • Synonyms
    D130012J15Rik, NTT4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442535
    NCBI Gene: 229706
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:107467548-107518018 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 46.83 cM, cytoband F2.3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    453 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442535
protein coding gene Chr3:107467543-107518018 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027749
protein coding gene Chr3:108961512-109010554 (-)
A/J MGP_AJ_G0027709
protein coding gene Chr3:105513069-105561786 (-)
AKR/J MGP_AKRJ_G0027674
protein coding gene Chr3:108086210-108137107 (-)
BALB/cJ MGP_BALBcJ_G0027721
protein coding gene Chr3:105203869-105254304 (-)
C3H/HeJ MGP_C3HHeJ_G0027451
protein coding gene Chr3:108427242-108477911 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028165
protein coding gene Chr3:113048901-113098982 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025503
protein coding gene Chr3:101665389-101714119 (-)
CAST/EiJ MGP_CASTEiJ_G0026907
protein coding gene Chr3:107805497-107856582 (-)
CBA/J MGP_CBAJ_G0027426
protein coding gene Chr3:116874085-116930732 (-)
DBA/2J MGP_DBA2J_G0027568
protein coding gene Chr3:104706949-104756556 (-)
FVB/NJ MGP_FVBNJ_G0027536
protein coding gene Chr3:102584844-102635592 (-)
LP/J MGP_LPJ_G0027675
protein coding gene Chr3:110386115-110437080 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027566
protein coding gene Chr3:122984038-123038823 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028220
protein coding gene Chr3:107683696-107731736 (-)
PWK/PhJ MGP_PWKPhJ_G0026633
protein coding gene Chr3:104441124-104491385 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026453
protein coding gene Chr3:105805023-105855303 (-)
WSB/EiJ MGP_WSBEiJ_G0026987
protein coding gene Chr3:108207795-108259338 (-)



Homology
more
  • Human Ortholog
    SLC6A17, solute carrier family 6 member 17
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC6A17, solute carrier family 6 member 17
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MRT48, NTT4
  • Links
    NCBI Gene ID: 388662
    neXtProt AC: NX_Q9H1V8
    UniProt: Q9H1V8

  • Chr Location
    1p13.3; chr1:110150510-110202202 (+)  GRCh38.p7

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 229706 NCBI Gene Model | MGI Sequence Detail 50471 C57BL/6J ±  kb
transcript NM_001293689 RefSeq | MGI Sequence Detail 6335 C57BL/6  
polypeptide Q8BJI1 UniProt | EBI | MGI Sequence Detail 727 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000015183 sodium-dependent neutral amino acid transporter SLC6A17
  • InterPro Domains
    IPR000175 Sodium:neurotransmitter symporter
    IPR002438 Sodium:neurotransmitter symporter, orphan
    IPR037272 Sodium:neurotransmitter symporter superfamily
Molecular
Reagents
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  • All nucleic 35
    Genomic 2
    cDNA 32
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139986
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:220477 Iqbal Z, et al., Homozygous SLC6A17 mutations cause autosomal-recessive intellectual disability with progressive tremor, speech impairment, and behavioral problems. Am J Hum Genet. 2015 Mar 5;96(3):386-96

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory