Lrfn3
Gene Detail

Symbol Name ID

Lrfn3 leucine rich repeat and fibronectin type III domain containing 3 MGI:2442512

Synonyms

A530045B06Rik, SALM4

Feature Type

protein coding gene

Genetic Map

Chromosome 7

17.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr7:30355514-30362772 bp, - strand From NCBI annotation of GRCm38   7259 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:11558  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Lrfn3

Human homologs

Human Homolog		LRFN3, leucine rich repeat and fibronectin type III domain containing 3
NCBI Gene ID		79414
neXtProt AC		NX_Q9BTN0
Human Synonyms		FIGLER1, SALM4
Human Chr (Location)		19q13.12; chr19:36428022-36436097 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(1) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	cell adhesion
Component	cell junction, cell projection, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (75)    Tissues (65)    Images (9)
Theiler Stages: 6, 8, 9, 11, 13, 15, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	40
Northern blot	35

cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(20) cDNA(18) Primer pair(1) Other(1)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000036957 (Evidence)
Entrez Gene	233067 (Evidence)
UniGene	23157
DFCI	TC1584425, TC1595301
DoTS	DT.94250346
NIA Mouse Gene Index	U028380
Consensus CDS Project	CCDS21088.1
International Mouse Knockout Project Status	Lrfn3

Sequences

Length	Strain/Species
genomic	233067	NCBI Gene Model | MGI Sequence Detail	7259	C57BL/6J
transcript	NM_175478	RefSeq | MGI Sequence Detail	2861	C57BL/6
polypeptide	Q8BLY3	UniProt | EBI | MGI Sequence Detail	626	Not Applicable

All sequences(20) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(27 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000483	Cysteine-rich flanking region, C-terminal
InterPro	IPR003961	Fibronectin, type III
InterPro	IPR013098	Immunoglobulin I-set
InterPro	IPR007110	Immunoglobulin-like domain
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003598	Immunoglobulin subtype 2
InterPro	IPR000372	Leucine-rich repeat-containing N-terminal
InterPro	IPR003591	Leucine-rich repeat, typical subtype
Protein Ontology	PR:000030889	leucine-rich repeat and fibronectin type-III domain-containing protein 3

Graphical View of Protein Domain Structure

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:165063 Mah W, et al., Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation. J Neurosci. 2010 Apr 21;30(16):5559-68
All references(27)