Cnpy1 MGI Mouse Gene Detail - MGI:2442451 - canopy FGF signaling regulator 1

Symbol

Cnpy1
Name

canopy FGF signaling regulator 1
Synonyms

1500012D20Rik, 9630008K15Rik

Feature Type

protein coding gene
IDs

MGI:2442451
NCBI Gene: 269637
Alliance

gene page
Transcription Start Sites

15 TSS

Sequence Map

Chr5:28200819-28245788 bp, - strand
From NCBI annotation of GRCm38

View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 13.99 cM
Mapping Data

2 experiments

SNPs within 2kb

130 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2442451	protein coding gene	Chr5:28200819-28245806 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0029370	protein coding gene	Chr5:26109790-26151179 (-)
A/J	MGP_AJ_G0029336	protein coding gene	Chr5:25219932-25268974 (-)
AKR/J	MGP_AKRJ_G0029287	protein coding gene	Chr5:26256517-26303525 (-)
BALB/cJ	MGP_BALBcJ_G0029347	protein coding gene	Chr5:25776717-25821056 (-)
C3H/HeJ	MGP_C3HHeJ_G0029068	protein coding gene	Chr5:26299800-26345144 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0029800	protein coding gene	Chr5:27715140-27760435 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027038	protein coding gene	Chr5:22837464-22882087 (-)
CAST/EiJ	MGP_CASTEiJ_G0028479	protein coding gene	Chr5:25404718-25445100 (-)
CBA/J	MGP_CBAJ_G0029036	protein coding gene	Chr5:28214514-28259298 (-)
DBA/2J	MGP_DBA2J_G0029185	protein coding gene	Chr5:25443570-25491146 (-)
FVB/NJ	MGP_FVBNJ_G0029143	protein coding gene	Chr5:24887361-24930152 (-)
LP/J	MGP_LPJ_G0029270	protein coding gene	Chr5:26554181-26598279 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029172	protein coding gene	Chr5:29245760-29304037 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029834	protein coding gene	Chr5:25894579-25939475 (-)
PWK/PhJ	MGP_PWKPhJ_G0028203	protein coding gene	Chr5:24567979-24614628 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0028034	protein coding gene	Chr5:25165201-25205010 (-)
WSB/EiJ	MGP_WSBEiJ_G0028559	protein coding gene	Chr5:25884799-25927788 (-)

Human Ortholog

CNPY1, canopy FGF signaling regulator 1

Vertebrate Orthologs

7

Human Ortholog

CNPY1, canopy FGF signaling regulator 1
Orthology source: HomoloGene, HGNC
Links

HGNC:27786

NCBI Gene ID: 285888

neXtProt AC: NX_Q3B7I2

UniProt: Q3B7I2
Chr Location

7q36.3; chr7:155501258-155533844 (-) GRCh38.p7

HomoloGene

Vertebrate Homology Class 89678
1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 macaque, rhesus
HCOP

human homology predictions: CNPY1
Gene Tree

Cnpy1

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References

2 with disease annotations

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
33 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

25
Chemically induced (other)

2
Gene trapped

17
Radiation induced

4
Spontaneous

1
Targeted

1
Genomic Mutations

7 involving Cnpy1
Incidental Mutations

APF
Find Mice (IMSR)

19 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

1
GO References

1

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell death	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	nucleic acid-templated transcription	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

29
Tissues

9
cDNA Data

10
Literature Summary

6

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase cnpy1

ZFIN cnpy1

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Cnpy1 interacts with 292 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

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All Sequences

50
RefSeq

4
UniProt

4
CCDS

CCDS19144.1, CCDS80237.1

Ensembl

ENSMUSG00000044681 (Evidence)
NCBI Gene

269637

			Length	Strain/Species	Flank
genomic	269637	NCBI Gene Model \| MGI Sequence Detail	44970	C57BL/6J	± kb
transcript	NM_001310511	RefSeq \| MGI Sequence Detail	3760	C57BL/6
polypeptide	Q4VAB4	UniProt \| EBI \| MGI Sequence Detail	94	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000005658 protein canopy homolog 1

(term hierarchy)
InterPro Domains

IPR021852 Domain of unknown function DUF3456

IPR042415 Protein canopy homolog

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All nucleic 13

cDNA 11

Primer pair 1

Other 1

Microarray probesets 5

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MGI:1925577, MGI:2141000

Summaries

All 60

Developmental Gene Expression 6

Diseases 2

Gene Ontology 1

Phenotypes 33
Earliest

J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
Latest

J:259186 Heng X, et al., Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6

TSS for Cnpy1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr50451	Chr5:28237879-28237888 (-)	7,904 bp
Tssr50450	Chr5:28210414-28210428 (-)	35,367 bp
Tssr50449	Chr5:28210398-28210405 (-)	35,386 bp
Tssr50448	Chr5:28210392-28210396 (-)	35,394 bp
Tssr50447	Chr5:28210170-28210179 (-)	35,613 bp
Tssr50446	Chr5:28210087-28210100 (-)	35,694 bp
Tssr50445	Chr5:28210067-28210082 (-)	35,713 bp
Tssr50444	Chr5:28210047-28210055 (-)	35,737 bp
Tssr50443	Chr5:28210031-28210034 (-)	35,755 bp
Tssr50442	Chr5:28209961-28209979 (-)	35,818 bp
Tssr50441	Chr5:28209916-28209935 (-)	35,862 bp
Tssr50440	Chr5:28209904-28209914 (-)	35,879 bp
Tssr50439	Chr5:28209843-28209862 (-)	35,935 bp
Tssr50438	Chr5:28209818-28209829 (-)	35,964 bp
Tssr50437	Chr5:28209747-28209764 (-)	36,032 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 08/13/2019 MGI 6.14