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Tmx3 Gene Detail
Summary
  • Symbol
    Tmx3
  • Name
    thioredoxin-related transmembrane protein 3
  • Synonyms
    6430411B10Rik, A730024F05Rik, mKIAA1830, Txndc10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442418
    NCBI Gene: 67988
  • Gene Overview
    MyGene.info: TMX3
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:90510154-90543267 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 59.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    76 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442418
protein coding gene Chr18:90510154-90543267 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024619
protein coding gene Chr18:91871823-91907462 (+)
A/J MGP_AJ_G0024586
protein coding gene Chr18:87751113-87783804 (+)
AKR/J MGP_AKRJ_G0024557
protein coding gene Chr18:90384620-90419895 (+)
BALB/cJ MGP_BALBcJ_G0024584
protein coding gene Chr18:88079115-88112287 (+)
C3H/HeJ MGP_C3HHeJ_G0024353
protein coding gene Chr18:90630597-90665433 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025032
protein coding gene Chr18:94250148-94291161 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022462
protein coding gene Chr18:86356169-86388423 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0024323
protein coding gene Chr18:97632372-97671508 (+)
DBA/2J MGP_DBA2J_G0024452
protein coding gene Chr18:87385500-87418480 (+)
FVB/NJ MGP_FVBNJ_G0024419
protein coding gene Chr18:86638833-86672452 (+)
LP/J MGP_LPJ_G0024537
protein coding gene Chr18:91808736-91849240 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024449
protein coding gene Chr18:99653194-99695420 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025080
protein coding gene Chr18:90731388-90766398 (+)
PWK/PhJ MGP_PWKPhJ_G0023571
protein coding gene Chr18:87665075-87699927 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023378
protein coding gene Chr18:90572953-90607918 (+)
WSB/EiJ MGP_WSBEiJ_G0023888
protein coding gene Chr18:90600995-90636088 (+)



Homology
more
  • Human Ortholog
    TMX3, thioredoxin related transmembrane protein 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMX3, thioredoxin related transmembrane protein 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PDIA13, TXNDC10
  • Links
    NCBI Gene ID: 54495
    neXtProt AC: NX_Q96JJ7
    UniProt: Q96JJ7

  • Chr Location
    18q22.1; chr18:68673688-68715116 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67988 NCBI Gene Model | MGI Sequence Detail 33114 C57BL/6J ±  kb
transcript NM_198295 RefSeq | MGI Sequence Detail 4611 C57BL/6  
polypeptide Q8BXZ1 UniProt | EBI | MGI Sequence Detail 456 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 10
Other
Accession IDs
less
MGI:1915238, MGI:2147338
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:45709 Melloy PG, et al., No turning, a mouse mutation causing left-right and axial patterning defects. Dev Biol. 1998 Jan 1;193(1):77-89
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory