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Nfrkb Gene Detail
Summary
  • Symbol
    Nfrkb
  • Name
    nuclear factor related to kappa B binding protein
  • Synonyms
    A530090G11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442410
    NCBI Gene: 235134
  • Gene Overview
    MyGene.info: NFRKB
Location & Maps
more
  • Sequence Map
    Chr9:31386192-31421333 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      35142 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 16.86 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NFRKB, nuclear factor related to kappaB binding protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NFRKB, nuclear factor related to kappaB binding protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    INO80G
  • Links
    NCBI Gene ID: 4798
    neXtProt AC: NX_Q6P4R8

  • Chr Location
    11q24-q25; chr11:129863773-129895595 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 4492
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: NFRKB
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034118 VEGA Gene Model | MGI Sequence Detail 35142 C57BL/6J ±  kb
transcript OTTMUST00000086311 VEGA | MGI Sequence Detail 5161 Not Applicable  
polypeptide OTTMUSP00000046720 VEGA | MGI Sequence Detail 1296 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    136 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000011183 nuclear factor related to kappa-B-binding protein
  • InterPro Domains
    IPR025220 NFRKB winged helix-like domain
    IPR024867 Nuclear factor related to kappa-B-binding protein
Molecular
Reagents
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  • All nucleic 101
    cDNA 100
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory